Organoid-guided precision hepatology for metabolic liver disease
S Osonoi, T Takebe - Journal of Hepatology, 2024 - Elsevier
Metabolic dysfunction associated steatotic liver disease affects millions of people worldwide.
Progress towards a definitive cure has been incremental and limited to only lifestyle …
Progress towards a definitive cure has been incremental and limited to only lifestyle …
[HTML][HTML] The role of novel adipokines and adipose-derived extracellular vesicles (ADEVs): connections and interactions in liver diseases
L Xie, H Wang, J Hu, Z Liu, F Hu - Biochemical Pharmacology, 2024 - Elsevier
Adipose tissues (AT) are an important endocrine organ that secretes various functional
adipokines, peptides, non-coding RNAs, and acts on AT themselves or other distant tissues …
adipokines, peptides, non-coding RNAs, and acts on AT themselves or other distant tissues …
[HTML][HTML] Pegbelfermin in patients with nonalcoholic steatohepatitis and compensated cirrhosis (FALCON 2): a randomized phase 2b study
MF Abdelmalek, AJ Sanyal, A Nakajima… - Clinical …, 2024 - Elsevier
Background & Aims Pegbelfermin is a polyethylene glycol–conjugated analog of human
fibroblast growth factor 21, a nonmitogenic hormone that regulates energy metabolism. This …
fibroblast growth factor 21, a nonmitogenic hormone that regulates energy metabolism. This …
[HTML][HTML] Pegbelfermin in patients with nonalcoholic steatohepatitis and stage 3 fibrosis (FALCON 1): A randomized phase 2b study
Background & Aims Pegbelfermin is a polyethlene glycol–conjugated analog of human
fibroblast growth factor 21, a nonmitogenic hormone that regulates energy metabolism. This …
fibroblast growth factor 21, a nonmitogenic hormone that regulates energy metabolism. This …
The Emerging Role of Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Metabolic-Dysfunction Associated Steatohepatitis
LA Abushamat, PA Shah, RH Eckel, SA Harrison… - Clinical …, 2024 - Elsevier
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects one in three to four
adult individuals and can progress to metabolic dysfunction-associated steatohepatitis …
adult individuals and can progress to metabolic dysfunction-associated steatohepatitis …
Hepatoprotection of capsaicin in alcoholic and non-alcoholic fatty liver diseases
E Karimi-Sales, G Mohaddes… - Archives of Physiology …, 2024 - Taylor & Francis
Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are common
causes of chronic liver disease that share the range of steatosis, steatohepatitis, fibrosis …
causes of chronic liver disease that share the range of steatosis, steatohepatitis, fibrosis …
Impact of Helicobacter pylori and metabolic syndrome on mast cell activation-related pathophysiology and neurodegeneration
Both Helicobacter pylori (H. pylori) infection and metabolic syndrome (MetS) are highly
prevalent worldwide. The emergence of relevant research suggesting a pathogenic linkage …
prevalent worldwide. The emergence of relevant research suggesting a pathogenic linkage …
Apigenin-6-C-glucoside ameliorates MASLD in rodent models via selective agonism of Adiponectin receptor 2
S Khatoon, N Das, S Chattopadhyay… - European Journal of …, 2024 - Elsevier
Adiponectin plays key roles in energy metabolism and ameliorates inflammation, oxidative
stress, and mitochondrial dysfunction via its primary receptors, adiponectin receptors-1 and …
stress, and mitochondrial dysfunction via its primary receptors, adiponectin receptors-1 and …
Implications of Protein and Sarcopenia in the Prognosis, Treatment, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
A Singh, A Buckholz, S Kumar, C Newberry - Nutrients, 2024 - mdpi.com
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is a common cause of
chronic liver disease globally, with prevalence rapidly increasing in parallel with rising rates …
chronic liver disease globally, with prevalence rapidly increasing in parallel with rising rates …
Separating the effects of early and later life body mass index on liver diseases: A Mendelian randomization study
F Zhou, X Liu, C Chang, J Liu, S He, Y Yan - Clinics and Research in …, 2024 - Elsevier
Background and aim The independent effects of childhood and adult body mass index (BMI)
on non-alcoholic fatty liver disease (NAFLD), cirrhosis, and hepatocellular carcinoma (HCC) …
on non-alcoholic fatty liver disease (NAFLD), cirrhosis, and hepatocellular carcinoma (HCC) …