Recent Progress in Nucleic Acid Pulmonary Delivery toward Overcoming Physiological Barriers and Improving Transfection Efficiency
Q Wang, C Bu, Q Dai, J Chen, R Zhang… - Advanced …, 2024 - Wiley Online Library
Pulmonary delivery of therapeutic agents has been considered the desirable administration
route for local lung disease treatment. As the latest generation of therapeutic agents, nucleic …
route for local lung disease treatment. As the latest generation of therapeutic agents, nucleic …
Building respirable powder architectures: utilizing polysaccharides for precise control of particle morphology for enhanced pulmonary drug delivery
K Kadota, H Uchiyama, T Kämäräinen… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Dry powder inhaler (DPI) formulations are gaining attention as universal
formulations with applications in a diverse range of drug formulations. The practical …
formulations with applications in a diverse range of drug formulations. The practical …
[HTML][HTML] Synergistic combination of antimicrobial peptide and isoniazid as inhalable dry powder formulation against multi-drug resistant tuberculosis
Z Shao, KKG Tam, VPK Achalla, ECY Woon… - International Journal of …, 2024 - Elsevier
Multidrug-resistant tuberculosis (MDR-TB) has posed a serious threat to global public
health, and antimicrobial peptides (AMPs) have emerged to be promising candidates to …
health, and antimicrobial peptides (AMPs) have emerged to be promising candidates to …
[HTML][HTML] Spray-drying of PEI-/PPI-based nanoparticles for DNA or siRNA delivery
S Noske, M Karimov, M Krüger, B Lilli, A Ewe… - European Journal of …, 2024 - Elsevier
Spray-drying of nucleic acid-based drugs designed for gene therapy or gene knockdown is
associated with many advantages including storage stability and handling as well as the …
associated with many advantages including storage stability and handling as well as the …
[HTML][HTML] Effect of leucine as an aerosolization enhancer on the bioactivity of spray dried viral-vectored vaccines for inhalation
Aerosolization enhancers, like L-leucine, can improve deep-lung deposition of inhalable dry
powders although the implications of their use have not yet been evaluated for sensitive …
powders although the implications of their use have not yet been evaluated for sensitive …
[PDF][PDF] Development of an Inhalable Dry Powder Platform for mRNA Therapeutics
J Schembera - 2024 - macau.uni-kiel.de
Development of an Inhalable Dry Powder Platform for mRNA Therapeutics Page 1 Development
of an Inhalable Dry Powder Platform for mRNA Therapeutics Dissertation zur Erlangung des …
of an Inhalable Dry Powder Platform for mRNA Therapeutics Dissertation zur Erlangung des …