Embracing Complexity: What Novel Sequencing Methods Are Teaching Us About Herpesvirus Genomic Diversity

A Ortigas-Vasquez, M Szpara - Annual Review of Virology, 2024 - annualreviews.org
The arrival of novel sequencing technologies throughout the past two decades has led to a
paradigm shift in our understanding of herpesvirus genomic diversity. Previously …

Loss to gain: pseudogenes in microorganisms, focusing on eubacteria, and their biological significance

Y Yang, P Wang, SE Qaidi, PR Hardwidge… - Applied Microbiology …, 2024 - Springer
Pseudogenes are defined as “non-functional” copies of corresponding parent genes. The
cognition of pseudogenes continues to be refreshed through accumulating and updating …

Autologous T-Cell-Free Antigen Presentation System Unveils HCMV-Specific NK Cell Response

MO Ustiuzhanina, MA Streltsova, ND Timofeev… - Cells, 2024 - mdpi.com
NK cells play a decisive role in controlling hCMV infection by combining innate and adaptive-
like immune reactions. The hCMV-derived VMAPRTLFL (LFL) peptide is a potent activator of …

[HTML][HTML] Multiple introductions of monkeypox virus to Ireland during the international mpox outbreak, May 2022 to October 2023

G Gonzalez, M Carr, TM Kelleher, E O'Byrne… - …, 2024 - eurosurveillance.org
Background Mpox, caused by monkeypox virus (MPXV), was considered a rare zoonotic
disease before May 2022, when a global epidemic of cases in non-endemic countries led to …

Human cytomegalovirus glycoprotein variants governing viral tropism and syncytium formation in epithelial cells and macrophages

G Cimato, X Zhou, W Brune, G Frascaroli - Journal of Virology, 2024 - Am Soc Microbiol
Human cytomegalovirus (HCMV) displays a broad cell tropism, and the infection of
biologically relevant cells such as epithelial, endothelial, and hematopoietic cells supports …

Cellular Transformation by Human Cytomegalovirus

G Herbein - Cancers, 2024 - mdpi.com
Simple Summary Discovering new oncoviruses is a main goal of virology research. In
addition to its deleterious role in immunocompromised patients and during pregnancy …

[HTML][HTML] Human Cytomegalovirus and Neonatal Infection

SM Lawrence - Current Research in Microbial Sciences, 2024 - Elsevier
Human cytomegalovirus is an ancient virus that has co-evolved with humans. It establishes
a life-long infection in suspectable individuals for which there is no vaccination or cure. The …

Human cytomegalovirus (HCMV) genetic diversity, drug resistance testing and prevalence of the resistance mutations: A literature review

I Grgic, L Gorenec - Tropical Medicine and Infectious Disease, 2024 - mdpi.com
Human cytomegalovirus (HCMV) is a pathogen with high prevalence in the general
population that is responsible for high morbidity and mortality in immunocompromised …

Bidirectional transfer of human cytomegalovirus strains in donor and recipient seropositive lung transplant patients

B Külekci, M Mollik, S Schwarz… - Journal of Medical …, 2024 - Wiley Online Library
Donor and recipient human cytomegalovirus (HCMV) seropositive (D+ R+) lung transplant
recipients (LTRs) often harbor multiple strains of HCMV, likely due to transmitted donor (D) …

Urinary cytomegalovirus excretion: the unresolved issues

L Puget, J Node, B Caël, J Bamoulid… - Annales …, 2024 - Elsevier
Cytomegalovirus (CMV) excretion in urine is frequently observed in clinical practice.
However, the specific circumstances and pathophysiological mechanisms underlying this …