Validation of biomarkers of aging
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
Pregnancy is linked to faster epigenetic aging in young women
CP Ryan, NR Lee, DB Carba… - Proceedings of the …, 2024 - National Acad Sciences
A central prediction of evolutionary theory is that energy invested into reproduction comes at
the expense of somatic maintenance and repair, accelerating biological aging. Supporting …
the expense of somatic maintenance and repair, accelerating biological aging. Supporting …
The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy …
Abstract The Semmelweis Study is a prospective occupational cohort study that seeks to
enroll all employees of Semmelweis University (Budapest, Hungary) aged 25 years and …
enroll all employees of Semmelweis University (Budapest, Hungary) aged 25 years and …
Reversal of biological age in multiple rat organs by young porcine plasma fraction
Young blood plasma is known to confer beneficial effects on various organs in mice and
rats. However, it was not known whether plasma from young adult pigs rejuvenates old rat …
rats. However, it was not known whether plasma from young adult pigs rejuvenates old rat …
Sex differences in biological aging and the association with clinical measures in older adults
Females live longer than males, and there are sex disparities in physical health and disease
incidence. However, sex differences in biological aging have not been consistently reported …
incidence. However, sex differences in biological aging have not been consistently reported …
Epigenetic aging and rheumatoid arthritis
N Mukherjee, TC Harrison - The Journals of Gerontology: Series …, 2024 - academic.oup.com
This is the first known comparative assessment of the associations of epigenetic age
estimates with the prevalence of rheumatoid arthritis (RA). We used data available in Gene …
estimates with the prevalence of rheumatoid arthritis (RA). We used data available in Gene …
Association of neighborhood deprivation and depressive symptoms with epigenetic age acceleration: evidence from the Canadian longitudinal study on aging
Background Neighborhood deprivation and depression have been linked to epigenetic age
acceleration. The next-generation epigenetic clocks including the DNA methylation (DNAm) …
acceleration. The next-generation epigenetic clocks including the DNA methylation (DNAm) …
Deciphering the role of immune cell composition in epigenetic age acceleration: Insights from cell‐type deconvolution applied to human blood epigenetic clocks
Aging is a significant risk factor for various human disorders, and DNA methylation clocks
have emerged as powerful tools for estimating biological age and predicting health‐related …
have emerged as powerful tools for estimating biological age and predicting health‐related …
[HTML][HTML] Exposure to ambient temperature and heat index in relation to DNA methylation age: a population-based study in Taiwan
KC Chiu, MS Hsieh, YT Huang, CY Liu - Environment International, 2024 - Elsevier
Background Climate change caused an increase in ambient temperature in the past
decades. Exposure to high ambient temperature could result in biological aging, but relevant …
decades. Exposure to high ambient temperature could result in biological aging, but relevant …
DNA methylation clocks for estimating biological age in Chinese cohorts
Z Zheng, J Li, T Liu, Y Fan, QC Zhai, M Xiong… - Protein & …, 2024 - academic.oup.com
Epigenetic clocks are accurate predictors of human chronological age based on the analysis
of DNA methylation (DNAm) at specific CpG sites. However, a systematic comparison …
of DNA methylation (DNAm) at specific CpG sites. However, a systematic comparison …