[HTML][HTML] The immune response to SARS-CoV-2 in people with HIV

MA Höft, WA Burgers, C Riou - Cellular & Molecular Immunology, 2024 - nature.com
This review examines the intersection of the HIV and SARS-CoV-2 pandemics. People with
HIV (PWH) are a heterogeneous group that differ in their degree of immune suppression …

[HTML][HTML] The Influence of Cross-Reactive T Cells in COVID-19

PJ Eggenhuizen, JD Ooi - Biomedicines, 2024 - mdpi.com
Memory T cells form from the adaptive immune response to historic infections or
vaccinations. Some memory T cells have the potential to recognise unrelated pathogens like …

[HTML][HTML] Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2

G Safont, R Villar-Hernández, D Smalchuk… - Scientific Reports, 2024 - nature.com
The study of specific T-cell responses against SARS-CoV-2 is important for understanding
long-term immunity and infection management. The aim of this study was to assess the dual …

[HTML][HTML] Primary prophylaxis with mTOR inhibitor enhances T cell effector function and prevents heart transplant rejection during talimogene laherparepvec therapy of …

V Joo, K Abdelhamid, A Noto, S Latifyan… - Nature …, 2024 - nature.com
The application of mammalian target of rapamycin inhibition (mTORi) as primary
prophylactic therapy to optimize T cell effector function while preserving allograft tolerance …

[HTML][HTML] Initial COVID-19 severity influenced by SARS-CoV-2-specific T cells imprints T-cell memory and inversely affects reinfection

G Yang, J Cao, J Qin, X Mei, S Deng, Y Xia… - … and Targeted Therapy, 2024 - nature.com
The immunoprotective components control COVID-19 disease severity, as well as long-term
adaptive immunity maintenance and subsequent reinfection risk discrepancies across initial …

Clinical and immunological features of COVID‐19 in patients with anti‐MDA5 dermatomyositis during the omicron wave in Chongqing, China

N Wu, Z Chen, G Zha, Z Deng, W Huang… - Journal of Medical …, 2024 - Wiley Online Library
Patients with anti‐melanoma differentiation‐associated gene 5 (anti‐MDA5)
dermatomyositis (DM) have a higher risk of coronavirus disease 2019 (COVID‐19) infection …

[HTML][HTML] The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine

X Chen, A Mohapatra, HTV Nguyen… - PLoS …, 2024 - journals.plos.org
Antibody-mediated immunity plays a key role in protection against SARS-CoV-2. We
characterized B-cell-derived anti-SARS-CoV-2 RBD antibody repertoires from vaccinated …

[HTML][HTML] Targeting TFH cells is a novel approach for donor-specific antibody desensitization of allograft candidates: an in vitro and in vivo study

N Ma, WB Wu, XY Zhao, LP Xu, XH Zhang… - …, 2024 - ncbi.nlm.nih.gov
The presence of donor-specific antibodies (DSA) are associated with graft failure either
following human leukocyte antigen (HLA)-mismatched allogeneic stem cell transplantation …

Impact of the immune profiles of hypertensive patients with and without obesity on COVID-19 severity

R Moll-Bernardes, JR Ferreira, AS Sousa… - International Journal of …, 2024 - nature.com
Background Comorbidities such as obesity, hypertension, and diabetes are associated with
COVID-19 development and severity, probably due to immune dysregulation; however, the …

[HTML][HTML] The immunobiology of SARS-CoV-2 infection and vaccine responses: potential influences of cross-reactive memory responses and aging on efficacy and off …

CP Collins, DL Longo, WJ Murphy - Frontiers in Immunology, 2024 - frontiersin.org
Immune responses to both SARS-CoV-2 infection and its associated vaccines have been
highly variable within the general population. The increasing evidence of long-lasting …