Psoriasis and atopic dermatitis fall within the category of cutaneous immune-mediated
inflammatory diseases (IMIDs). The prevalence of IMIDs is increasing in industrialized …

As chronic inflammatory conditions driven by immune dysregulation are influenced by
genetics and environment factors, psoriasis and atopic dermatitis (AD) have traditionally …

Abstract Background Postinfectious Lyme arthritis (LA) is associated with dysregulated
immunity and autoreactive T-and B-cell responses in joints. Here we explored the role of …

Eosinophilic esophagitis (EoE) is a rare atopic disorder associated with esophageal
dysfunction, including difficulty swallowing, food impaction, and inflammation, that develops …

Background Multiple treatment options are available for the management of psoriasis, but
clinical response varies among individual patients and no biomarkers are available to …

Psoriasis is a complex inflammatory skin disease characterized by reversible albeit
relapsing red scaly plaques in the skin of a patient. In addition to the genetic predisposition …

As a vital immune organ, skin performs multiple physiological functions. Immune skin
diseases (ISDs), characterized by dysregulated immune responses, manifested as abnormal …

Psoriasis is a multifactorial genetic disorder manifested by hyperproliferation and abnormal
differentiation of epidermal keratinocytes, along with the infiltration of inflammatory cells into …

Regulatory elements, particularly enhancers, play a crucial role in disease susceptibility and
progression. Enhancers are DNA sequences that activate gene expression and can be …

ABSTRACT A subgroup of atopic dermatitis (AD) patients suffers from recurrent,
disseminated herpes simplex virus (HSV) skin infections, eczema herpeticum (EH). To …