Advances in uromodulin biology and potential clinical applications

A Nanamatsu, L de Araújo, KA LaFavers… - Nature Reviews …, 2024 - nature.com
Uromodulin (also known as Tamm–Horsfall protein) is a kidney-specific glycoprotein
secreted bidirectionally into urine and into the circulation, and it is the most abundant protein …

The versatile role of uromodulin in renal homeostasis and its relevance in chronic kidney disease

T Takata, H Isomoto - Internal Medicine, 2024 - jstage.jst.go.jp
Uromodulin, also known as the Tamm-Horsfall protein, is predominantly expressed in
epithelial cells of the kidney. It is secreted mainly in the urine, although small amounts are …

The development of lateral flow devices for urinary biomarkers to assess kidney health

SD Souza, W Obeid, J Hernandez, D Hu, Y Wen… - Scientific reports, 2024 - nature.com
Serum creatinine levels are insensitive to real-time changes in kidney function or injury.
There is a growing interest in assessing kidney injury by measuring biomarkers in body fluid …

Association of serum copeptin and urinary uromodulin with kidney function, blood pressure and albuminuria at 6 weeks post-partum in pre-eclampsia

DA Jaques, A Dufey Teso, G Wuerzner… - Frontiers in …, 2024 - frontiersin.org
Background Preeclampsia (PE) is associated with subsequent higher risk of cardiovascular
and kidney disease. Serum copeptin, as a proxy for vasopressin, and urinary uromodulin …

[HTML][HTML] Serum and Urinary Uromodulin in Dogs with Early Chronic Kidney Disease vs. Healthy Canine Population

N Marečáková, J Kačírová, C Tóthová, A Maďari… - Animals, 2024 - mdpi.com
Simple Summary Simple Summary: Uromodulin has been known for many years as a
normal protein component of urine. However, in recent years, serum as well as urinary …

[PDF][PDF] ROLE OF SERUM UROMODULIN AS A BIOMARKER OF DECLINE IN RENAL FUNCTION IN CHRONIC KIDNEY DISEASE

S Ananth, MS Sharma, PLVP Reddy… - International Journal of …, 2024 - ijmedph.org
Background: Uromodulin (Tamm–Horsfall protein), the most common protein in normal urine
present in a bundant quantity, is increasingly considered as a potential biomarker relevant to …

Оценка роли альбуминурии и уромодулина в ранней диагностике нарушений функций почек при некоторых фенотипах ожирения

АГ Гадаев, РК Дадабаева - Нефрология, 2024 - journal.nephrolog.ru
Аннотация Цель: изучение взаимосвязи биологических маркеров, отражающих
поражения почек с их функциональным состоянием, а также с клиническими …