Targeting the epigenetically older individuals for geroprotective trials: The use of DNA methylation clocks
E Sandalova, AB Maier - Biogerontology, 2024 - Springer
Chronological age is the most important risk factor for the incidence of age-related diseases.
The pace of ageing determines the magnitude of that risk and can be expressed as …
The pace of ageing determines the magnitude of that risk and can be expressed as …
Gene therapy-mediated partial reprogramming extends lifespan and reverses age-related changes in aged mice
Aging is a complex progression of changes best characterized as the chronic dysregulation
of cellular processes leading to deteriorated tissue and organ function. Although aging …
of cellular processes leading to deteriorated tissue and organ function. Although aging …
[HTML][HTML] Exposure to ambient temperature and heat index in relation to DNA methylation age: a population-based study in Taiwan
KC Chiu, MS Hsieh, YT Huang, CY Liu - Environment International, 2024 - Elsevier
Background Climate change caused an increase in ambient temperature in the past
decades. Exposure to high ambient temperature could result in biological aging, but relevant …
decades. Exposure to high ambient temperature could result in biological aging, but relevant …
Where are we in the implementation of tissue-specific epigenetic clocks?
Introduction: DNA methylation clocks presents advantageous characteristics with respect to
the ambitious goal of identifying very early markers of disease, based on the concept that …
the ambitious goal of identifying very early markers of disease, based on the concept that …
Blood-Based Epigenetic Age Acceleration and Incident Colorectal Cancer Risk: Findings from a Population-Based Case–Control Study
S Malyutina, O Chervova, V Maximov… - International Journal of …, 2024 - mdpi.com
This study investigates the association between epigenetic age acceleration (EAA) derived
from DNA methylation and the risk of incident colorectal cancer (CRC). We utilized data from …
from DNA methylation and the risk of incident colorectal cancer (CRC). We utilized data from …