AI-based Advanced approaches and dry eye disease detection based on multi-source evidence: Cases, applications, issues, and future directions

MH Wang, L Xing, Y Pan, F Gu, J Fang… - Big Data Mining and …, 2024 - ieeexplore.ieee.org
This study explores the potential of Artificial Intelligence (AI) in early screening and
prognosis of Dry Eye Disease (DED), aiming to enhance the accuracy of therapeutic …

Potential New Target for Dry Eye Disease—Oxidative Stress

J Bu, Y Liu, R Zhang, S Lin, J Zhuang, L Sun, L Zhang… - Antioxidants, 2024 - mdpi.com
Dry eye disease (DED) is a multifactorial condition affecting the ocular surface. It is
characterized by loss of tear film homeostasis and accompanied by ocular symptoms that …

Engineering Ultra‐Small Cerium‐Based Metal–Organic Frameworks Nanozymes for Efficient Antioxidative Treatment of Dry Eye Disease

Z Chen, Z Li, N Tang, Y Huang, S Li… - Advanced Functional …, 2024 - Wiley Online Library
Dry eye disease (DED) is a widespread ophthalmic illness that inflicts massive economic
and medical burdens on society. Although oxidative stress is closely associated with the …

A Preservative-Free Approach–Effects on Dry Eye Signs and Symptoms After Cataract Surgery

P Jensen, C Nilsen, M Gundersen… - Clinical …, 2024 - Taylor & Francis
Purpose To compare the effect of treatment with preservative-free dexamethasone, NSAIDs
and trehalose/hyaluronic acid eye drops with the preservative benzalkonium chloride …

Membrane Fusion‐Mediated Loading of Therapeutic siRNA into Exosome for Tissue‐Specific Application

M Xie, Y Wu, Y Zhang, R Lu, Z Zhai, Y Huang… - Advanced …, 2024 - Wiley Online Library
Tissue‐specific delivery of oligonucleotide therapeutics beyond the liver remains a key
challenge in nucleic acid drug development. To address this issue, exploiting exosomes as …

Efficacy of topical 0.05% cyclosporine A and 0.1% sodium hyaluronate in post-refractive surgery chronic dry eye patients with ocular pain

L Zhao, J Chen, H Duan, T Yang, B Ma, Y Zhou… - BMC …, 2024 - Springer
Background The management of post-refractive surgery dry eye disease (DED) can be
challenging in clinical practice, and patients usually show an incomplete response to …

Association of Dry Eye Symptoms and Signs in Patients with Dry Eye Disease

A Tawfik, M Pistilli, MG Maguire, Y Chen… - Ophthalmic …, 2024 - Taylor & Francis
Purpose To determine the correlations among symptoms and signs of dry eye disease
(DED) in the Dry Eye Assessment and Management (DREAM) study. Methods A total of 535 …

Dry Eye Disease in the Middle East and Northern Africa: a position paper on the current state and unmet needs

S Lazreg, M Hosny, MA Ahad, MM Sinjab… - Clinical …, 2024 - Taylor & Francis
Abstract In the Middle East and Northern Africa (MENA), dry eye disease (DED) is often
misdiagnosed or overlooked. This review summarizes a series of conversations with …

Comparing two mucin secretagogues for the treatment of dry eye disease: a prospective randomized crossover trial

Y Jin, KY Seo, SW Kim - Scientific Reports, 2024 - nature.com
This study aimed to compare the clinical efficacy and investigate patients' preferences for
two mucin secretagogues in the treatment of dry eye disease (DED). Thirty patients with …

Polarity-Driven Fluorescence Monitoring of Lipid Droplet Dynamics in Dry Eye Disease

JT Hou, C Li, S Guo, X Ye, W Chi, Y Ren… - Analytical …, 2024 - ACS Publications
The emergence of lipid droplets (LDs) has been recognized as cellular markers of ocular
surface hyperosmosis, which is recognized as a fundamental mechanism driving dry eye …