Millions of people worldwide have chronic kidney disease (CKD). Affected patients are at
high risk for cardiovascular (CV) disease for several reasons. Among various comorbidities …

Abstract Measuring SARS-CoV-2-specific T cell responses is crucial to understanding an
individual's immunity to COVID-19. However, high inter-and intra-assay variability make it …

Despite prolonged surveillance and interventions, the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and influenza viruses continue to pose a severe global health …

Introduction During the COVID-19 pandemic, EMA set-up a large-scale cohort event
monitoring (CEM) system to estimate incidence rates of patient-reported adverse drug …

Third doses of COVID-19 vaccines were widely deployed following the primary vaccine
course waning and the emergence of the Omicron-variant. We investigated protection from …

Background Methotrexate is the first-line treatment for immune-mediated inflammatory
diseases and reduces vaccine-induced immunity. We evaluated if a 2-week interruption of …

We study a multi-objective pure exploration problem in a multi-armed bandit model. Each
arm is associated to an unknown multi-variate distribution and the goal is to identify the …

Background Whether human T-lymphotropic virus type 1 (HTLV-1) carriers can develop
sufficient humoral immunity after coronavirus disease 2019 (COVID-19) vaccination is …

Adenoviral and mRNA vaccines encoding the viral spike (S) protein have been deployed
globally to contain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Older …

Background COVID-19 vaccines used in humans are highly effective in limiting disease and
death caused by the SARS-CoV-2 virus, yet improved vaccines that provide greater …