The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has substantially damaged the global economy and human health. The …

Durable humoral immunity is mediated by long-lived plasma cells (LLPCs) that reside in the
bone marrow. It remains unclear whether severe acute respiratory syndrome coronavirus 2 …

Coronavirus disease 2019 (COVID-19), which is caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a global pandemic. The …

The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has resulted in the loss
of millions of lives and severe global economic consequences. Every time SARS-CoV-2 …

Omicron, as the emerging variant with enhanced vaccine tolerance, has sharply disrupted
most therapeutic antibodies. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Background High-risk patients, often immunocompromised and not responding to vaccine,
continue to experience severe coronavirus disease 2019 (COVID-19) and death …

Summary Background SARS-CoV-2-neutralizing antibodies (nABs) showed great promise
in the early phases of the COVID-19 pandemic. The emergence of resistant strains …

Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) utilizes angiotensin-
converting enzyme 2 (ACE2) as its main receptor for cell entry. We bioengineered a soluble …

The global evolution of SARS-CoV-2 depends in part upon the evolutionary dynamics within
individual hosts with varying immune histories. To characterize the within-host evolution of …

Abstract Background Central Michigan University (CMU) participated in a state-wide SARS-
CoV-2 wastewater monitoring program since 2021. Wastewater samples were collected …