Programmed Remodeling of the Tumor Milieu to Enhance NK Cell Immunotherapy Combined with Chemotherapy for Pancreatic Cancer

X Yang, C Li, H Yang, T Li, S Ling, Y Zhang, F Wu… - Nano Letters, 2024 - ACS Publications
Natural killer (NK) cell-based adoptive immunotherapy has demonstrated encouraging
therapeutic effects in clinical trials for hematological cancers. However, the effectiveness of …

Multiscale elasticity mapping of biological samples in 3D at optical resolution

K Regan, R LeBourdais, R Banerji, S Zhang… - Acta Biomaterialia, 2024 - Elsevier
The mechanical properties of biological tissues have emerged as an integral determinant of
tissue function in health and disease. Nonetheless, characterizing the elasticity of biological …

[HTML][HTML] Phenotypic Heterogeneity, Bidirectionality, Universal Cues, Plasticity, Mechanics, and the Tumor Microenvironment Drive Cancer Metastasis

CT Mierke - Biomolecules, 2024 - mdpi.com
Tumor diseases become a huge problem when they embark on a path that advances to
malignancy, such as the process of metastasis. Cancer metastasis has been thoroughly …

Concomitant use of renin-angiotensin system inhibitors augments the efficacy of immune checkpoint inhibitors: a systematic review and meta-analysis

J Yu, F Meng, W Sui, J Yu, J Shen - Frontiers in Pharmacology, 2024 - frontiersin.org
Background The impact of renin-angiotensin system inhibitors (RASIs) on the outcome of
hypertensive cancer patients undergoing immune checkpoint inhibitor (ICIs) therapy …

[HTML][HTML] Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity

L Peng, L Zhou, H Li, X Zhang, S Li, K Wang, M Yang… - Cell Reports, 2024 - cell.com
The major histocompatibility complex class I (MHC class I)-mediated tumor antigen
processing and presentation (APP) pathway is essential for the recruitment and activation of …

Isolation and Characterization of a Novel Mammary Adenocarcinoma, MCa-P1362, with Hormone Receptor Expression, Human Epidermal Growth Factor Receptor 2 …

S Jana, W Li, PJ Lei, Z Wang, S Kibara, P Huang… - The American Journal of …, 2024 - Elsevier
Preclinical models that display spontaneous metastasis are necessary to improve the
therapeutic options for hormone receptor–positive breast cancers. Within this study, detailed …

[HTML][HTML] Predicting three or more metastatic nodes using contrast-enhanced lymphatic US findings in early breast cancer

Z Niu, Y Hao, Y Gao, J Zhang, M Xiao, F Mao… - Insights into …, 2024 - Springer
Objectives To develop and validate a nomogram for predicting≥ 3 metastatic axillary lymph
nodes (ALNs) in early breast cancer with no palpable axillary adenopathy by …

[HTML][HTML] Clinical factors and major pathological response after neoadjuvant chemoimmunotherapy in potentially resectable lung squamous cell carcinoma

Y Wang, Y Song, R Wang, Y Wu, M Li, K Xu… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Objective Major pathological response (MPR) helps evaluate the prognosis of patients with
lung squamous cell carcinoma (LUSC). However, the clinical factors that affect the …

Alteration of mechanical stresses in the murine brain by age and hemorrhagic stroke

S Zheng, R Banerji, R LeBourdais, S Zhang… - PNAS …, 2024 - academic.oup.com
Residual mechanical stresses, also known as solid stresses, emerge during rapid
differential growth or remodeling of tissues, as observed in morphogenesis and tumor …

Differential diagnosis of cervical lymphadenopathy: Integration of postvascular phase of contrast-enhanced ultrasound and predictive nomogram model

X Chen, J Ma, Y Fu, F Mei, R Tang, H Xue, Y Lin… - European Journal of …, 2024 - Elsevier
Background Distinguishing benign from malignant cervical lymph nodes is critical yet
challenging. This study evaluates the postvascular phase of contrast-enhanced ultrasound …