Immunological nanomaterials to combat cancer metastasis

Y Pan, J Cheng, Y Zhu, J Zhang, W Fan… - Chemical Society …, 2024 - pubs.rsc.org
Metastasis causes greater than 90% of cancer-associated deaths, presenting huge
challenges for detection and efficient treatment of cancer due to its high heterogeneity and …

Custom‐Design of Multi‐Stimuli‐Responsive Degradable Silica Nanoparticles for Advanced Cancer‐Specific Chemotherapy

J Zhang, J Zhou, L Tang, J Ma, Y Wang, H Yang… - Small, 2024 - Wiley Online Library
Chemotherapy is crucial in oncology for combating malignant tumors but often encounters
obatacles such as severe adverse effects, drug resistance, and biocompatibility issues. The …

Targeting Vascular Destruction by Sonosensitizer‐Free Sonocatalytic Nanomissiles Instigates Thrombus Aggregation and Nutrition Deprivation to Starve Pancreatic …

Y He, T Wang, Y Song, C Fang, Y Wang… - Advanced Functional …, 2024 - Wiley Online Library
Sonosensitizers in current sonodynamic therapy (SDT) often suffer from poor delivery
efficiency, phototoxicity, and disputed safety. To overcome these issues, a sonosensitizers …

Theranostic Fluorescent Probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Precise modulation and use of reactive oxygen species for immunotherapy

X Li, J Gao, C Wu, C Wang, R Zhang, J He, ZJ Xia… - Science …, 2024 - science.org
Reactive oxygen species (ROS) play an important role in regulating the immune system by
affecting pathogens, cancer cells, and immune cells. Recent advances in biomaterials have …

[HTML][HTML] Programmed microalgae-gel promotes chronic wound healing in diabetes

Y Kang, L Xu, J Dong, X Yuan, J Ye, Y Fan… - Nature …, 2024 - nature.com
Chronic diabetic wounds are at lifelong risk of developing diabetic foot ulcers owing to
severe hypoxia, excessive reactive oxygen species (ROS), a complex inflammatory …

Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …

A Distinctive Insight into Inorganic Sonosensitizers: Design Principles and Application Domains

W Qin, Q Yang, C Zhu, R Jiao, X Lin, C Fang, J Guo… - Small, 2024 - Wiley Online Library
Sonodynamic therapy (SDT) as a promising non‐invasive anti‐tumor means features the
preferable penetration depth, which nevertheless, usually can't work without …

Injectable Responsive Hydrogel Delivery Platform: Enabling High Tissue Penetration and Sonogenetic‐Like Potentiating Anti‐Tumor Immunotherapy

Z Dai, X Li, Q Chen, Y Zhu, Z Shi… - Advanced Functional …, 2024 - Wiley Online Library
The characteristics of malignant solid tumors with dense extracellular matrix (ECM) and
immunosuppressive microenvironment (IME) seriously restrict the high efficacy and precise …

The pH-dependent multiple nanozyme activities of copper-cerium dioxide and its application in regulating intracellular oxygen and hydrogen peroxide levels

J Liu, Y Zhu, Y Fan, L Gong, X Zhu, Y Zhang… - Journal of Colloid and …, 2024 - Elsevier
Abstract Cu doped CeO 2 (Cu-CeO 2) nanoparticles were synthesized via the hydrothermal
method, exhibiting multiple nanozyme activities such as good oxidase-like (OXD) …