Removal of innate immune barriers allows efficient transduction of quiescent human hematopoietic stem cells
Quiescent human hematopoietic stem cells (HSC) are ideal targets for gene therapy
applications due to their preserved stemness and repopulation capacities; however, they …
applications due to their preserved stemness and repopulation capacities; however, they …
Molecular dynamics investigation of DNA fragments bound to the anti-HIV protein SAMHD1 reveals alterations in allosteric communications
G Thapa, A Bhattacharya, S Bhattacharya - Journal of Molecular Graphics …, 2024 - Elsevier
The sterile alpha motif and histidine-aspartate domain-containing protein 1 (or SAMHD1), a
human dNTP-triphosphohydrolase, contributes to HIV-1 restriction in select terminally …
human dNTP-triphosphohydrolase, contributes to HIV-1 restriction in select terminally …