The role of biomarkers in the diagnosis and management of pneumonia

S Sungurlu, RA Balk - Infectious Disease Clinics, 2024 - id.theclinics.com
The Role of Biomarkers in the Diagnosis and Management of Pneumonia - Infectious
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[HTML][HTML] Analytical micro and nano technologies meet sepsis diagnosis

JMG Pidal, Á Molinero-Fernández… - TrAC Trends in …, 2024 - Elsevier
Sepsis is one of the deadliest health disorders in the current century due to specific
limitations in early and differential diagnosis. Therefore, early diagnosis and appropriate …

Elevations in presepsin, PCT, hs-CRP, and IL-6 levels predict mortality among septic patients in ICU

Y Zhou, Y Feng, X Liang, S Gui, D Ren… - Journal of Leukocyte …, 2024 - academic.oup.com
Background Aim to investigate the predictive value of changes in presepsin (PSEP),
procalcitonin (PCT), high-sensitivity C-reactive protein (hsCRP), and interleukin-6 (IL-6) …

Diagnostic Accuracy of Procalcitonin in Bacterial Infections of the CNS: An Updated Systematic Review, Meta-Analysis, and Meta-Regression

DG Biasucci, PG Sergi, F Bilotta, M Dauri - Critical Care Medicine, 2024 - journals.lww.com
OBJECTIVES: To evaluate diagnostic accuracy of serum and cerebrospinal fluid (CSF)
procalcitonin for diagnosing CNS bacterial infections. DATA SOURCES: We searched …

Exploring the Impact of Model-Informed Precision Dosing on Procalcitonin Concentrations in Critically Ill Patients: A Secondary Analysis of the DOLPHIN Trial

S Dräger, TMJ Ewoldt, A Abdulla, WJR Rietdijk… - Pharmaceutics, 2024 - mdpi.com
Model-informed precision dosing (MIPD) might be used to optimize antibiotic treatment.
Procalcitonin (PCT) is a biomarker for severity of infection and response to antibiotic …

[HTML][HTML] Evaluation of Serial Procalcitonin Levels for the Optimization of Antibiotic Use in Non-Critically Ill COVID-19 Patients

AS Almulhim, MA Alabdulwahed, FF Aldoughan… - Pharmaceuticals, 2024 - mdpi.com
Background: Procalcitonin (PCT) has been used as a biomarker to guide antibiotic therapy
in various patient populations. However, its role in optimizing antibiotic use in COVID-19 …

Mortality prediction model from combined serial lactate, procalcitonin and calprotectin levels in critically ill patients with sepsis: A retrospective study according to …

LG de Guadiana-Romualdo, LA Botella… - Medicina Intensiva …, 2024 - Elsevier
Objective 1) To evaluate the ability of baseline and on 24 h serum calprotectin, in
comparison to canonical biomarkers (lactate and procalcitonin), for prognosis of 28-day …

Analytical Evaluation of Point-of-Care Finecare™ Procalcitonin Rapid Quantitative Test in Sepsis Population as Compared with Elecsys® BRAHMS Procalcitonin …

MZ Mazlan, WN Wan Azman, NM Yaacob, TS Koon… - Diagnostics, 2024 - mdpi.com
The study compared two plasma procalcitonin (PCT) assays, the point of care (POC)
Finecare™ Procalcitonin Rapid Quantitative Test and the Elecsys® BRAHMS PCT …

Omic approaches to infectious disease testing

RE Mahle, EL Tsalik - Molecular Medical Microbiology, 2024 - Elsevier
A pathogen-based approach to infectious disease diagnosis has long been the gold
standard, despite poor sensitivity, specificity, or long time to result with this method. The host …

[HTML][HTML] Utility of Serum Procalcitonin and Its Clearance in Predicting Outcomes in COVID-19 Patients

N Mehfooz, TH Shah, F Siraj, SM Qadri, UH Khan… - Cureus, 2024 - ncbi.nlm.nih.gov
Methods We prospectively included 39 patients with severe or critical COVID-19 illness with
an age equal to more than 18 years. In addition to routine baseline investigations, serum …