Recent developments in chemodrug-loaded nanomedicines and their application in combination cancer immunotherapy

N Shim, H Cho, SI Jeon, K Kim - Journal of Pharmaceutical Investigation, 2024 - Springer
Background In recent studies of cancer therapies, chemodrugs have attracted interest,
acting not only as traditional chemotherapeutic agents but also as anticancer immune …

Therapeutic and diagnostic applications of carbon nanotubes in cancer: recent advances and challenges

M Sharma, P Alessandro… - Journal of Drug …, 2024 - Taylor & Francis
Carbon nanotubes (CNTs) are allotropes of carbon, composed of carbon atoms forming a
tube-like structure. Their high surface area, chemical stability, and rich electronic …

An innovative nanoformulation utilizing tumor microenvironment-responsive PEG-polyglutamic coating and dynamic charge adjustment for specific targeting of ER …

CY Li, TF Chou, YL Lo - International Journal of Biological Macromolecules, 2024 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a significant obstacle to lowering global
cancer deaths. CB-5083, a novel valosin-containing protein (VCP)/p97 inhibitor that disrupts …

Nitric oxide water-driven immunogenic cell death: Unfolding mitochondrial dysfunction's role in sensitizing lung adenocarcinoma to ferroptosis and autophagic cell …

M Negi, N Kaushik, P Lamichhane, P Patel… - Free Radical Biology …, 2024 - Elsevier
Non-small cell lung cancer (NSCLC), particularly lung adenocarcinoma (LUAD), significantly
influences cancer-related mortality and is frequently considered by poor therapeutic …

Durable Attenuation of Tumor pH–Platelet Linkage Reinstates Bioorthogonal Targeting of Residual Tumors Post-Debulking

P Zhang, B Li, Z Wang, J Li, F Wang, J Kong, Z Zhou… - ACS …, 2024 - ACS Publications
There are circumstances where tumors can only be partially resected. Therefore,
multimodality therapy targeting post-operative residuals is important. Here, we show that …

Bioinspired adhesive nanofibrous hydrogel promotes immune infiltration through effective immunochemotherapy for osteosarcoma treatment

CH Lee, WY Huang, KY Lee, CH Kuan, TC Wu… - Chemical Engineering …, 2024 - Elsevier
Osteosarcoma, the predominant primary malignant bone tumor, presents ongoing clinical
challenges, notably in local recurrence and metastasis. Here, we introduce a nanofibrous …

Role of HIF-1α in the Responses of Tumors to Radiotherapy and Chemotherapy

CW Song, H Kim, MS Kim, HJ Park, SH Paek… - Cancer Research and …, 2024 - e-crt.org
Tumor microenvironment is intrinsically hypoxic with abundant hypoxia-inducible factors-1α
(HIF-1α), a primary regulator of the cellular response to hypoxia and various stresses …