Several different reactive oxygen species (ROS) are generated in vivo. They have roles in
the development of certain human diseases whilst also performing physiological functions …

Vascular aging, featuring endothelial dysfunction and large elastic artery stiffening, is a
major risk factor for the development of age-associated cardiovascular diseases (CVDs) …

Exercise training prevents age‐related decline in muscle function. Targeting epigenetic
aging is a promising actionable mechanism and late‐life exercise mitigates epigenetic aging …

Objective To examine the association between the Mediterranean lifestyle and all-cause,
cancer, and cardiovascular disease (CVD) mortality in a British population. Patients and …

On average, aging is associated with unfavorable changes in cellular metabolism, which are
the processes involved in the storage and expenditure of energy. However, metabolic …

Age is a major risk factor for the development of cardiovascular diseases in men and in
women. However, not all people age at the same rate and those who are aging rapidly are …

Bedrest as an experimental paradigm or as an in-patient stay for medical reasons has
negative consequences for cardiovascular health. The effects of severe inactivity parallel …

This study investigated the effect of knockout of six Hsp70 genes (orthologues of the
mammalian genes Hspa1a, Hspa1b, Hspa2, and Hspa8) on age-related changes in gene …

Abstract Evaluation of the influence of primary and secondary aging on the manifestation of
molecular and cellular hallmarks of aging is a challenging and currently unresolved issue …

On 29–30 November 2023, the inaugural Global Healthspan Summit, convened in Riyadh
by the nonprofit Hevolution Foundation, provided a dynamic platform that united experts …