Inhibition of autophagosome-lysosome fusion contributes to TDCIPP-induced Aβ1-42 production in N2a-APPswe cells
C Zou, T Yang, X Huang, X Ren, C Yang, B Xu, J Liu - Heliyon, 2024 - cell.com
Alzheimer's disease is the most common form of dementia and is characterized by cognitive
impairment. The disruption of autophagosome-lysosome function has been linked to the …
impairment. The disruption of autophagosome-lysosome function has been linked to the …
mTORC3 activity is regulated by GSK3β through the activation of PKCδ that phosphorylates and activates STAT1.
J Zhan, FC Harwood, M Cardone, GC Grosveld - bioRxiv, 2024 - biorxiv.org
The mechanistic target of rapamycin serine/threonine kinase (mTOR), a critical regulator of
cell proliferation, is implicated in many human diseases, including cancer. Our laboratory …
cell proliferation, is implicated in many human diseases, including cancer. Our laboratory …