The gastrointestinal tract and Parkinson's disease

AS Higinbotham, CW Kilbane - Frontiers in cellular and infection …, 2024 - frontiersin.org
Parkinson's disease (PD) is the second most common (De Lau and Breteler, 2006) and the
most rapidly rising neurodegenerative disease in the world (GBD 2016 Parkinson's disease …

Regulation of Pain Perception by Microbiota in Parkinson Disease

Z Manjarres, M Calvo, R Pacheco - Pharmacological Reviews, 2024 - ASPET
Pain perception involves current stimulation in peripheral nociceptive nerves and the
subsequent stimulation of postsynaptic excitatory neurons in the spinal cord. Importantly, in …

Unveiling the Journey from the Gut to the Brain: Decoding Neurodegeneration–Gut Connection in Parkinson's Disease

K Bhardwaj, AA Singh, H Kumar - ACS Chemical Neuroscience, 2024 - ACS Publications
Parkinson's disease, a classical motor disorder affecting the dopaminergic system of the
brain, has been as a disease of the brain, but this classical notion has now been viewed …

The probiotic SLAB51 as agent to counteract BPA toxicity on zebrafish gut microbiota-liver-brain axis

C Giommi, M Lombó, HR Habibi, G Rossi… - Science of the Total …, 2024 - Elsevier
A plethora of studies have so far described the toxic effects of bisphenol A (BPA) on
organism health, highlighting the urgent need to find new strategies not only to reduce the …

Identification of Causal Relationships between Gut Microbiota and Influenza A Virus Infection in Chinese by Mendelian Randomization

Q Liao, F Wang, W Zhou, G Liao, H Zhang, Y Shu… - Microorganisms, 2024 - mdpi.com
Numerous studies have reported a correlation between gut microbiota and influenza A virus
(IAV) infection and disease severity. However, the causal relationship between these factors …

Emerging Insights into Postoperative Neurocognitive Disorders: The Role of Signaling Across the Gut-Brain Axis

W Yu, Z Zhu, F Tang - Molecular Neurobiology, 2024 - Springer
The pathophysiological regulatory mechanisms in postoperative neurocognitive disorders
(PNCDs) are intricately complex. Currently, the pathogenesis of PNCDs has not been fully …

Psychobiotics and the Microbiota–Gut–Brain Axis: Where Do We Go from Here?

S Binda, A Tremblay, UH Iqbal, O Kassem, M Le Barz… - Microorganisms, 2024 - mdpi.com
The bidirectional relationship between the gut microbiota and the nervous system is known
as the microbiota–gut–brain axis (MGBA). The MGBA controls the complex interactions …

Co-administration of probiotics and vitamin D reduced disease severity and complications in patients with Parkinson's disease: a randomized controlled clinical trial

A Zali, S Hajyani, M Salari, M Tajabadi-Ebrahimi… - …, 2024 - Springer
Rationale Probiotics have beneficial effects on the nervous system by modulating the gut-
brain axis. Additionally, vitamin D supplementation presents a potential way for ameliorating …

[HTML][HTML] Modulation of gut microbiota with probiotics as a strategy to counteract endogenous and exogenous neurotoxicity

AV Skalny, M Aschner, VA Gritsenko… - Advances in …, 2024 - ncbi.nlm.nih.gov
The existing data demonstrate that probiotic supplementation affords protective effects
against neurotoxicity of exogenous (eg, metals, ethanol, propionic acid, aflatoxin B1, organic …

The Effect of Gut Microbiota-Targeted Interventions on Neuroinflammation and Motor Function in Parkinson's Disease Animal Models—A Systematic Review

PȘ Panaitescu, V Răzniceanu… - Current Issues in …, 2024 - mdpi.com
Gut microbiome-targeted interventions such as fecal transplant, prebiotics, probiotics,
synbiotics, and antibiotic gut depletion are speculated to be of potential use in delaying the …