Exploring the properties and potential of the neural extracellular matrix for next‐generation regenerative therapies

JA Ortega, GP Soares de Aguiar… - Wiley …, 2024 - Wiley Online Library
The extracellular matrix (ECM) is a dynamic and complex network of proteins and molecules
that surrounds cells and tissues in the nervous system and orchestrates a myriad of …

Exploring Heparan Sulfate Proteoglycans as Mediators of Human Mesenchymal Stem Cell Neurogenesis

SI Petersen, RK Okolicsanyi, LM Haupt - Cellular and molecular …, 2024 - Springer
Alzheimer's disease (AD) and traumatic brain injury (TBI) are major public health issues
worldwide, with over 38 million people living with AD and approximately 48 million people …

Challenges and Future Perspectives in Modeling Neurodegenerative Diseases Using Organ‐on‐a‐Chip Technology

FM Pramotton, S Spitz, RD Kamm - Advanced Science, 2024 - Wiley Online Library
Neurodegenerative diseases (NDDs) affect more than 50 million people worldwide, posing
a significant global health challenge as well as a high socioeconomic burden. With aging …