Unconventional IFNω-like genes dominate the type I IFN locus and the constitutive antiviral responses in bats

R Geng, Q Wang, YL Yao, XR Shen, JK Jia… - The Journal of …, 2024 - journals.aai.org
Bats are the natural reservoir hosts of some viruses, some of which may spill over to humans
and cause global-scale pandemics. Different from humans, bats may coexist with high …

Identification of RBM39 as a key regulator of innate immune response, governing basal expression of IRF3 and other critical pathway components

T Li - 2024 - archiv.ub.uni-heidelberg.de
The cell intrinsic innate immune response serves as the first line of defense of a host cell
against microbial invasions. It initiates with the activation of pattern recognition receptors …