[HTML][HTML] Potential applications of artificial intelligence in image analysis in cornea diseases: a review

KY Tey, EZK Cheong, M Ang - Eye and Vision, 2024 - Springer
Artificial intelligence (AI) is an emerging field which could make an intelligent healthcare
model a reality and has been garnering traction in the field of medicine, with promising …

Accurate detection and grading of pterygium through smartphone by a fusion training model

Y Liu, C Xu, S Wang, Y Chen, X Lin, S Guo… - British Journal of …, 2024 - bjo.bmj.com
Background/aims To improve the accuracy of pterygium screening and detection through
smartphones, we established a fusion training model by blending a large number of slit …

Unravelling the molecular tapestry of pterygium: insights into genes for diagnostic and therapeutic innovations

M Gupta, S Arya, P Agrawal, H Gupta, R Sikka - Eye, 2024 - nature.com
Pterygium, an ocular surface disorder, manifests as a wing-shaped extension from the
corneoscleral limbus onto the cornea, impacting vision and causing inflammation. With a …

Single-cell RNA sequencing reveals the complex cellular niche of pterygium

X Zhang, P Han, J Qiu, F Huang, Q Luo, J Cheng… - The Ocular Surface, 2024 - Elsevier
Purpose Pterygium is a vision-threatening conjunctival fibrovascular degenerated disease
with a high global prevalence up to 12%, while no absolute pharmacotherapy has been …

Contribution of matrix metalloproteinase-2 genotypes to Taiwan pterygium risk

PS Hu, NY Hsia, ZH Wang, HC Chen, TC Hsia, ML Lin… - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: In the literature, the studies about the role of matrix metalloproteinase-2
(MMP-2) in pterygium diagnosis are mainly based on its protein expression. The role of …

[HTML][HTML] Evaluation of lymphotoxin-alpha in pterygium and diagnostic value in active and inactive pterygium states

G Lan, X Fang, Y Zhong, S Luo, X Xiao, Z Xie, L Luo… - Scientific Reports, 2024 - nature.com
To explore the correlation between tear LT-a, pterygium status, and dry eye indicators. We
established a diagnostic model to evaluate active pterygium. A retrospective study was …

[HTML][HTML] Low Rate of Postoperative Pterygium Recurrence in Patients under Treatment with Low-Dose Oral Doxycycline for Chronic Blepharitis: A First Report

F Catania, P Vinciguerra, A Di Maria - Diagnostics, 2024 - mdpi.com
Purpose: Low doses of systemic doxycycline (LD-SD) inhibit angiogenesis and the
expression of matrix metalloproteases, which are determinants of pterygium progression …

[HTML][HTML] Inflammation due to ocular surface homeostasis imbalance caused by pterygia: tear lymphotoxin-alpha study and a literature review

X Fang, G Lan, Y Lin, Z Xie, Y Zhong, S Luo… - Journal of Ophthalmic …, 2024 - Springer
Objective To estimate the pterygium ocular surface state, and compare with healthy eyes
and dry eyes. To investigate the inflammation due to pterygia growth by tear Lymphotoxin …

The effect of different pterygium surgery techniques on the ocular surface parameters in different durations: a systematic review and meta-analysis

J Chang, Q Cao, J Yong, X Ling, X Zhang… - Graefe's Archive for …, 2024 - Springer
Purpose To evaluate the effects of different pterygium surgery techniques on ocular surface
(OS) in different follow-up periods. Methods PubMed, Cochrane Library, Web of Science …

[HTML][HTML] A Phase IIa Multicenter, Randomized, Vehicle-Controlled, Dose Escalating Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of CBT-001 …

SM Whitcup, KN Sall, JA Hovanesian… - Ophthalmology …, 2024 - Elsevier
Purpose To evaluate the safety and efficacy of CBT-001, a multitarget tyrosine kinase
inhibitor eyedrop, for pterygia. Design Phase II clinical trial. Stage 1 was a single center …