Sodium alginate/polyvinyl alcohol nanofibers loaded with Shikonin for diabetic wound healing: In vivo and in vitro evaluation

C Ding, J Yang, N Wang, Q Ding, S Sun, Y Gao… - International journal of …, 2024 - Elsevier
Diabetic wounds are typically chronic wounds and the healing process is limited by
problems such as high blood glucose levels, bacterial infections, and other issues that make …

Research progress in mechanism of anticancer action of shikonin targeting reactive oxygen species

K Qi, J Li, Y Hu, Y Qiao, Y Mu - Frontiers in Pharmacology, 2024 - frontiersin.org
Excessive buildup of highly reactive molecules can occur due to the generation and
dysregulation of reactive oxygen species (ROS) and their associated signaling pathways …

Pharmacological Significance of Boraginaceae with Special Insights into Shikonin and Its Potential in the Food Industry

S Gautam, L Lapčík, B Lapčíková - Foods, 2024 - mdpi.com
Shikonin is a naphthoquinone pigment present in the hairy roots of the plant species from
the Boraginaceae family. The compound has been well investigated for its highly efficient …

Shikonin alleviates doxorubicin-induced cardiotoxicity via Mst1/Nrf2 pathway in mice

H Tuo, W Li, W Zhao, J Zhao, D Li, L Jin - Scientific Reports, 2024 - nature.com
Doxorubicin (DOX) is a popular and potent anticancer drug, but its cardiotoxicity limits its
clinical application. Shikonin has a wide range of biological functions, including antioxidant …

Shikonin in breast cancer treatment: a comprehensive review of molecular pathways and innovative strategies

S Iranzadeh, D Dalil, S Kohansal… - Journal of Pharmacy …, 2024 - academic.oup.com
Objectives Breast cancer is a prevalent disease that has a substantial impact on women's
mortality rates. Shikonin, a naphthoquinone derived from Lithospermum erythrorhizon, has …

Potential Efficacy of Shiunko for Anti-Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibody-Induced Skin Fissure: A Single Institutional Case Series

M Okunaka, D Kotani, S Mishima… - Integrative Cancer …, 2024 - journals.sagepub.com
Purpose: Anti-epidermal growth factor receptor monoclonal antibody (anti-EGFR mAb) is the
key drug for RAS/BRAF V600E wild-type metastatic colorectal cancer (mCRC). However …

Shikonin potentiates skin wound healing in Sprague–Dawley rats by stimulating fibroblast and endothelial cell proliferation and angiogenesis

C Xue, J Dou, S Zhang, H Yu… - The Journal of Gene …, 2024 - Wiley Online Library
Background Shikonin, a major component of Lithospermum erythrorhizon, exerts anti‐
inflammatory and antibacterial effects and expedites wound healing. This study aims to …

Cell Suspension Culture-Mediated Secondary Metabolites Production from Medicinal Plants with Antiallergy Properties

R Mitra, J Upadhyay, N Chakraborty - Biotechnology of Medicinal Plants …, 2024 - Springer
The increasing global prevalence of allergic diseases, affecting 20% of the population,
necessitates novel antiallergic treatments. Traditional medications, particularly H1-blockers …

Simulations de dynamique moléculaire à haute résolution des isoformes 1 et 2 de la pyruvate kinase musculaire

Q Delobelle - 2024 - theses.hal.science
Le métabolisme glycolytique joue un rôle essentiel dans les processus physiologiques
normaux et dans la croissance des cellules cancéreuses. Les isoformes 1 et 2 de la …

[引用][C] Фармакогностический анализ лекарственного растительного сырья Оносма Гмелина (Onosma gmelinii) и фармацевтическая разработка …

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