Recent advances in the treatment of Ebola disease: A brief overview

LEW El Ayoubi, O Mahmoud, J Zakhour… - Plos Pathogens, 2024 - journals.plos.org
Ebola disease (EBOD) remains a significant and ongoing threat to African countries,
characterized by a mortality rate of 25% to 90% in patients with high viral load and …

[HTML][HTML] RNAi-Induced Gene Silencing against Chikungunya and COVID-19: What Have We Learned So Far, and What Is the Way Forward?

K Panda, K Alagarasu, R Tagore, M Paingankar… - Viruses, 2024 - mdpi.com
RNA interference (RNAi) is a process in which small RNA molecules (such as small
interfering RNAs or siRNAs) bind to specific messenger RNAs (mRNAs), leading to its …

Impact of Ebola virus nucleoprotein on VP40 virus-like particle production: a computational approach

X Liu, RV Stahelin, E Pienaar - Communications Biology, 2024 - nature.com
Ebola virus (EBOV) matrix protein VP40 can assemble and bud as virus-like particles (VLPs)
when expressed alone in mammalian cells. Nucleoprotein (NP) could be recruited to VLPs …

Principle, application and challenges of development siRNA-based therapeutics against bacterial and viral infections: a comprehensive review

H Motamedi, MM Ari, A Alvandi, R Abiri - Frontiers in Microbiology, 2024 - frontiersin.org
While significant progress has been made in understanding and applying gene silencing
mechanisms and the treatment of human diseases, there have been still several obstacles in …

[HTML][HTML] Global Perspective on COVID-19 Therapies, Cardiovascular Outcomes, and Implications for Long COVID: A State-of-the-Art Review

A Sarfraz, Z Sarfraz, S Bano, M Sarfraz… - Journal of Community …, 2024 - ncbi.nlm.nih.gov
The COVID-19 pandemic has resulted in many therapies, of which many are repurposed
and used for other diseases in the last decade such in Influenza and Ebola. We intend to …

OPEN ACCESS EDITED AND REVIEWED BY

D Yang, N Jeganathan, N Jeganathan… - New Insights into …, 2024 - books.google.com
The Sustainable Development Goals (SDGs) established by the United Nations provide a
comprehensive framework for a brighter tomorrow, encompassing crucial aspects such as …

Validation of the STERIS Amsco 630LS steam sterilizer autoclave for inactivation of category a medical waste from patients with high-consequence infectious diseases

JA Tarabay, JS Morgan, CS Kraft… - Infection Control & …, 2024 - cambridge.org
Hospitals caring for patients with high-consequence pathogens may need to safely manage
large volumes of category A waste. Using biological indicators to assess for successful …

Development of RNAi-based antiviral therapeutic strategies

SS Ambike - 2024 - mediatum.ub.tum.de
Approximately 296 million individuals are chronically infected with hepatitis B virus globally.
Therapeutic vaccination could be a way to achieve cure. This study contributes to further …

Compendium: Management of Viral Hemorrhagic Fever (Viral Fever), Involving Its Pathogenesis

Y Srivastav, A Kumar, J Singh… - Asian Journal of …, 2024 - archives.articleproms.com
The term" Viral Hemorrhagic Fever"(VHF) describes a severe feverish sickness
characterized by aberrant vascular control, vascular damage, and hemorrhagic symptoms …

[PDF][PDF] A Review of Epidemiology of Viral Hemorrhagic Fever

Y Srivastav, MF Mansoori, VK Pandey - Disease and Health Research … - researchgate.net
The pathophysiology, aetiology, diagnosis, treatment, symptoms, and indicators of virus
hemorrhagic fevers (VHFs) are all covered in this review article. Acute zoonotic diseases …