Wastewater-based surveillance as a tool for public health action: SARS-CoV-2 and beyond

MD Parkins, BE Lee, N Acosta, M Bautista… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Wastewater-based surveillance (WBS) has undergone dramatic advancement in the context
of the coronavirus disease 2019 (COVID-19) pandemic. The power and potential of this …

Considerations and Opportunities for Probe Capture Enrichment Sequencing of Emerging Viruses from Wastewater

RS Kantor, M Jiang - Environmental Science & Technology, 2024 - ACS Publications
Until recently, wastewater-based monitoring for pathogens of public health concern primarily
used PCR-based quantification methods and targeted sequencing for specific pathogens …

Prevalence of SARS-CoV-2 variants in Prague wastewater determined by nanopore-based sequencing

A Dostálková, K Zdeňková, J Bartáčková, E Čermáková… - Chemosphere, 2024 - Elsevier
The early detection of upcoming disease outbreaks is essential to avoid both health and
economic damage. The last four years of COVID-19 pandemic have proven wastewater …

Timely monitoring of SARS-CoV-2 RNA fragments in wastewater shows the emergence of JN. 1 (BA. 2.86. 1.1, clade 23I) in Berlin, Germany

A Bartel, JH Grau, J Bitzegeio, D Werber, N Linzner… - Viruses, 2024 - mdpi.com
The importance of COVID-19 surveillance from wastewater continues to grow since case-
based surveillance in the general population has been scaled back world-wide. In Berlin …

High-resolution and real-time wastewater viral surveillance by Nanopore sequencing

X Xu, Y Deng, J Ding, Q Tang, Y Lin, X Zheng, T Zhang - Water Research, 2024 - Elsevier
Wastewater genomic sequencing stands as a pivotal complementary tool for viral
surveillance in populations. While long-read Nanopore sequencing is a promising platform …

Integrating wastewater and randomised prevalence survey data for national COVID surveillance

G Li, P Diggle, M Blangiardo - Scientific Reports, 2024 - nature.com
During the COVID-19 pandemic, studies in a number of countries have shown how
wastewater can be used as an efficient surveillance tool to detect outbreaks at much lower …

Systematic SARS-CoV-2 S-gene sequencing in wastewater samples enables early lineage detection and uncovers rare mutations in Portugal

AC Reis, D Pinto, S Monteiro, R Santos… - Science of the Total …, 2024 - Elsevier
As the COVID-19 pandemic reached its peak, many countries implemented genomic
surveillance systems to track the evolution and transmission of SARS-CoV-2. Transition from …

Breakthrough Infections in SARS-CoV-2-Vaccinated Multiple Myeloma Patients Improve Cross-Protection against Omicron Variants

A Wagner, E Garner-Spitzer, C Auer, P Gattinger… - Vaccines, 2024 - mdpi.com
Patients with multiple myeloma (MM) are a heterogenous, immunocompromised group with
increased risk for COVID-19 morbidity and mortality but impaired responses to primary …

Crykey: rapid identification of SARS-CoV-2 cryptic mutations in wastewater

Y Liu, N Sapoval, P Gallego-García, L Tomás… - Nature …, 2024 - nature.com
Wastewater surveillance for SARS-CoV-2 provides early warnings of emerging variants of
concerns and can be used to screen for novel cryptic linked-read mutations, which are co …

Estimating actual SARS-CoV-2 infections from secondary data

W Rauch, H Schenk, N Rauch, M Harders… - Scientific Reports, 2024 - nature.com
Eminent in pandemic management is accurate information on infection dynamics to plan for
timely installation of control measures and vaccination campaigns. Despite huge efforts in …