Elucidation of critical chemical moieties of metallo-β-lactamase inhibitors and prioritisation of target metallo-β-lactamases
JH Lee, SG Kim, KM Jang, K Shin, H Jin… - Journal of Enzyme …, 2024 - Taylor & Francis
The urgent demand for effective countermeasures against metallo-β-lactamases (MBLs)
necessitates development of novel metallo-β-lactamase inhibitors (MBLIs). This study is …
necessitates development of novel metallo-β-lactamase inhibitors (MBLIs). This study is …
Visible light‐mediated photocatalyzed synthesis of oxazole via intermolecular C N and C O bond formation
MZ Beg, S Tivari, A Kashyap, PK Singh… - Journal of …, 2024 - Wiley Online Library
An efficient visible light‐mediated, eosin Y‐catalyzed synthesis of oxazole has been
developed from benzil with primary amines, that providing a straightforward, green, and …
developed from benzil with primary amines, that providing a straightforward, green, and …
[HTML][HTML] Fluorinated captopril analogues inhibit metallo-β-lactamases and facilitate structure determination of NDM-1 binding pose
A Kondratieva, K Palica, C Frøhlich, RR Hovd… - European Journal of …, 2024 - Elsevier
Bacterial resistance to the majority of clinically used β-lactam antibiotics is a global health
threat and, consequently, the driving force for the development of metallo-β-lactamase …
threat and, consequently, the driving force for the development of metallo-β-lactamase …
Fluorescently Modified NDM-1: A Versatile Drug Sensor for Rapid In Vitro β-Lactam Antibiotic and Inhibitor Screening
SF Chung, SY Tam, WT Wong, PK So, WL Cheong… - ACS …, 2024 - ACS Publications
We successfully developed a fluorescent drug sensor from clinically relevant New Delhi
metallo-β-lactamase-1 (NDM-1). The F70 residue was chosen to be replaced with a cysteine …
metallo-β-lactamase-1 (NDM-1). The F70 residue was chosen to be replaced with a cysteine …
Synthesis, antifungal activity, 3D-QSAR, and molecular docking study of novel anethole-derived hydroxamate compounds
Y Cui, R Li, W Duan, B Cen, G Lin, K Wu - Phytochemistry Letters, 2024 - Elsevier
In an attempt to search for natural product-derived antifungal agents, a series of novel
anethole-derived hydroxamate compounds were designed and synthesized. Their chemical …
anethole-derived hydroxamate compounds were designed and synthesized. Their chemical …