Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases

M Kampmann - Nature Reviews Neuroscience, 2024 - nature.com
The selective vulnerability of specific neuronal subtypes is a hallmark of neurodegenerative
diseases. In this Review, I summarize our current understanding of the brain regions and …

Break-up and recovery of harmony between direct and indirect pathways in the basal ganglia: Huntington's disease and treatment

SY Kim, W Lim - Cognitive Neurodynamics, 2024 - Springer
The basal ganglia (BG) in the brain exhibit diverse functions for motor, cognition, and
emotion. Such BG functions could be made via competitive harmony between the two …

[HTML][HTML] Reduced inhibitory synaptic transmission onto striatopallidal neurons may underlie aging-related motor skill deficits

Q Shan, X Yu, X Lin, Y Tian - Neurobiology of Disease, 2024 - Elsevier
Human beings are living longer than ever before and aging is accompanied by an increased
incidence of motor deficits, including those associated with the neurodegenerative …