Biomarkers to guide medical therapy in primary aldosteronism

GL Hundemer, AA Leung, GA Kline… - Endocrine …, 2024 - academic.oup.com
Primary aldosteronism (PA) is an endocrinopathy characterized by dysregulated
aldosterone production that occurs despite suppression of renin and angiotensin II, and that …

Aldosterone and aldosterone synthase inhibitors in cardiorenal disease

S Verma, A Pandey, AK Pandey… - American Journal …, 2024 - journals.physiology.org
Modulation of the renin-angiotensin-aldosterone system is a foundation of therapy for
cardiovascular and kidney diseases. Excess aldosterone plays an important role in …

Treating primary aldosteronism-induced hypertension: novel approaches and future outlooks

N Mullen, J Curneen, PT Donlon, P Prakash… - Endocrine …, 2024 - academic.oup.com
Primary aldosteronism (PA) is the most common cause of secondary hypertension and is
associated with increased morbidity and mortality when compared with blood pressure …

The impact of superselective adrenal artery embolization on renal function in patients with primary aldosteronism: a prospective cohort study

ZQ Lai, Y Fu, JW Liu, HJ Zhang, H Zhang… - Hypertension …, 2024 - nature.com
Superselective adrenal artery embolization (SAAE) is an effective treatment for patients with
primary aldosteronism (PA). However, the impact of SAAE on renal function in the PA …

Aldosteronism is associated with more severe cerebral small vessel disease in hypertensive intracerebral hemorrhage

BC Lee, HH Tsai, ZW Chen, CC Chang… - Hypertension …, 2024 - nature.com
Primary aldosteronism is associated with various types of cardiovascular and
cerebrovascular damage independently of hypertension. Although chronic hypertension and …

Effects of esaxerenone on blood pressure, urinary albumin excretion, serum levels of NT-proBNP, and quality of life in patients with primary aldosteronism

Y Yoshida, M Fujiwara, M Kinoshita, K Sada… - Hypertension …, 2024 - nature.com
Primary aldosteronism (PA) is typically managed with mineralocorticoid receptor antagonists
(MRAs) barring adrenalectomy. The efficacy of esaxerenone, a nonsteroidal MRA, were …

Contralateral suppression in adrenal venous sampling predicts clinical and biochemical outcome in primary aldosteronism

J Okubo, P Frudit, ACBS Cavalcante… - The Journal of …, 2024 - academic.oup.com
Context The role of hormone parameters at adrenal venous sampling (AVS) in predicting
clinical and biochemical outcomes remains controversial. Objective To investigate the …

[HTML][HTML] Diagnosis and management of primary hyperaldosteronism in patients with hypertension: a practical approach endorsed by the British and Irish Hypertension …

L Faconti, S Kulkarni, C Delles, V Kapil… - Journal of Human …, 2024 - nature.com
Alongside the lack of homogeneity among international guidelines and consensus
documents on primary hyperaldosteronism, the National UK guidelines on hypertension do …

Evaluation of a Best-Practice Advisory for Primary Aldosteronism Screening

S Charoensri, L Bashaw, C Dehmlow… - JAMA Internal …, 2024 - jamanetwork.com
Importance Primary aldosteronism (PA) is a common cause of secondary hypertension and
an independent risk factor for cardiovascular morbidity and mortality. Fewer than 2% to 4 …

[HTML][HTML] Treatment of primary aldosteronism: clinical practice guidelines of the Taiwan Society of Aldosteronism

CS Tseng, CK Chan, HY Lee, CT Pan, KY Peng… - Journal of the Formosan …, 2024 - Elsevier
Primary aldosteronism (PA) is the most common cause of secondary hypertension and one
of the few medical diseases that can be cured by surgery. Excessive aldosterone secretion …