Host Factors Modulate Virus-Induced IFN Production via Pattern Recognition Receptors

J Wang, Y Dong, X Zheng, H Ma, M Huang… - Journal of …, 2024 - Taylor & Francis
Innate immunity is the first line of defense in the human body, and it plays an important role
in defending against viral infection. Viruses are identified by different pattern-recognition …

PZR suppresses innate immune response to RNA viral infection by inhibiting MAVS activation in interferon signaling mediated by RIG-I and MDA5

R Deng, L Zhang, S Chen, X Li, B Xue, H Li, Y Xu… - Antiviral Research, 2024 - Elsevier
RNA viral infections seriously endanger human health. Src homology 2 (SH2) domain-
containing protein tyrosine phosphatase 2 (SHP2) suppresses innate immunity against …