N-of-1 medicine

P Wang, QY Leong, NY Lau, WY Ng… - Singapore Medical …, 2024 - journals.lww.com
The fields of precision and personalised medicine have led to promising advances in
tailoring treatment to individual patients. Examples include genome/molecular alteration …

CURATE. AI—artificial intelligence‐derived personalized tacrolimus dosing for pediatric liver transplant: a retrospective study

SB Tan, K Senthil Kumar, TRX Gan… - Advanced …, 2024 - Wiley Online Library
Tacrolimus is the cornerstone of immunosuppressive therapy after pediatric liver
transplantation. However, reliance on the physician's experience for dose titration, coupled …

Discovery of Broad‐Spectrum Repurposed Drug Combinations Against Carbapenem‐Resistant Enterobacteriaceae (CRE) Through Artificial Intelligence (AI)‐Driven …

M Li, K You, P Wang, L Hooi, Y Chen… - Advanced …, 2024 - Wiley Online Library
Antimicrobial resistance challenges the sustainability of healthcare systems and results in
substantial economic losses worldwide. This issue is further aggravated by paucity of new …

Dynamic, personalized dose selection platform, CURATE. AI, in patients with solid tumors: case series and pilot feasibility trial

R Sundar, A Blasiak, A Truong, L Tan, KS Kumar… - 2024 - researchsquare.com
In oncology, the conventional reliance on maximum tolerated doses (MTD) strategy for
chemotherapy may not optimize treatment outcomes for individual patients. Artificial …