Effects of gene polymorphisms on delayed MTX clearance, toxicity, and metabolomic changes after HD-MTX treatment in children with acute lymphoblastic leukemia

Y Zhou, H He, L Ding, T Wang, X Liu, M Zhang… - European Journal of …, 2024 - Springer
This study aims to assess the role of methotrexate-related gene polymorphisms in children
with acute lymphoblastic leukemia (ALL) during high-dose methotrexate (HD-MTX) therapy …

Association between genetic polymorphisms in SLC19A1, SLCO1B1 and SLCO1B3 genes predicts survival and toxicity in North Indian lung cancer patients …

P Sharma, N Singh, S Sharma - Authorea Preprints, 2024 - advance.sagepub.com
Aims: SLC transporters are expressed in lungs and are essential membrane proteins
responsible for the transport of wide range of chemotherapeutic drugs. Polymorphisms in …