Nanotherapeutics for prostate cancer treatment: A comprehensive review

R Hu, J Lan, D Zhang, W Shen - Biomaterials, 2024 - Elsevier
Prostate cancer (PCa) is the most prevalent solid organ malignancy and seriously affects
male health. The adverse effects of prostate cancer therapeutics can cause secondary …

[HTML][HTML] Targeted anti-tumor synergistic effects of Myc decoy oligodeoxynucleotides-loaded selenium nanostructure combined with chemoradiotherapy on LNCaP …

R Ghorbani, M Gharbavi, A Sharafi, E Rismani… - Oncology …, 2024 - ncbi.nlm.nih.gov
In the present study, we investigated the synergistic effects of targeted methotrexate-
selenium nanostructure containing Myc decoy oligodeoxynucleotides along with X …

[HTML][HTML] Prostate specific membrane antigen (PSMA) avid nonprostatic benign and malignant disease: a pictorial review

R Srinivasan, GJR Cook, N Patel, M Subesinghe - Clinical Radiology, 2024 - Elsevier
Highlights•PSMA is a transmembrane glycoprotein highly expressed in prostate cancer
(PC).•PSMA PET-CT is revolutionising PC management in staging and biochemical …

Discovery of Glutamate Carboxypeptidase III Ligands to Compete the Uptake of [177Lu]Lu-PSMA-617 in Healthy Organs

M Müller, L Lucaroni, N Favalli, G Bassi… - Journal of Medicinal …, 2024 - ACS Publications
Prostate-specific membrane antigen (PSMA)-targeted radio ligand therapeutics (RLTs), such
as [177Lu] Lu-PSMA-617 (Pluvicto), have been shown to accumulate in salivary glands and …

Synthesis and preclinical evaluation of 68Ga-labeled PSMA tracers with improved pharmacological properties

H Hou, Y Lin, Y Pan, Y Ma, G Hou, X Sun… - European Journal of …, 2024 - Elsevier
Prostate cancer (PCa) is one of the most common tumors in men, with the overexpression of
prostate-specific membrane. In this study, we developed four new 68 Ga-labeled PSMA …

Enhancing the anticancer effect of androgen deprivation therapy by monocarboxylate transporter 1 inhibitor in prostate cancer cells

J Kim, S Park, S Kim, S Ryu, H Hwang, S Cho… - The …, 2024 - Wiley Online Library
Background Tumor initiation and progression necessitate a metabolic shift in cancer cells.
Consequently, the progression of prostate cancer (PCa), a leading cause of cancer‐related …

[HTML][HTML] Intrahepatic cholangiocarcinoma detected on 18F-PSMA-1007 PET/MR imaging in a prostate cancer patient: a case report and literature review

Y Sun, H Wang, Y Yang, Z You, J Zhao - Frontiers in Oncology, 2024 - ncbi.nlm.nih.gov
Radionuclide probes-targeted prostate-specific membrane antigen (PSMA) is used in
diagnosis and treatment of prostate cancer (PCa). Recent studies have shown that PSMA is …

Prostate-specific membrane antigen-PET/CT may result in stage migration in prostate cancer: performances, quantitative analysis, and potential criticism in the clinical …

P Alongi, M Messina, A Pepe, A Arnone… - Nuclear Medicine …, 2024 - journals.lww.com
Aim The early detection of prostate cancer (PCa) metastatic disease with PET imaging leads
to stage migration and change of disease management. We aimed to assess the impact on …

“One Method to Label Them All”: A Single Fully Automated Protocol for GMP-Compliant 68Ga Radiolabeling of PSMA-11, Transposable to PSMA-I&T and PSMA-617

J Fouillet, C Donzé, E Deshayes… - Current …, 2024 - ingentaconnect.com
Background: Prostate-specific membrane antigen (PSMA) is an ideal target for molecular
imaging and targeted radionuclide therapy in prostate cancer. Consequently, various PSMA …

3.1 A BRIEF INTRODUCTION TO BIOLOGY OF CANCER AND CANCER METASTASIS

A Hull, J Forster, S Tronchin… - Radiotheranostics-A Primer …, 2024 - books.google.com
According to the World Health Organization (WHO)," cancer is a leading cause of death
worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths"[1] …