Prevention of vascular contributions to cognitive impairment and dementia: the role of physical activity and exercise

E Dao, CK Barha, J Zou, N Wei, T Liu-Ambrose - Stroke, 2024 - Am Heart Assoc
Vascular contributions to cognitive impairment and dementia, specifically cerebral small
vessel disease (CSVD), are the second most common cause of dementia. Currently, there …

Current and future treatments of vascular cognitive impairment

BYM Ip, H Ko, BYK Lam, LWC Au, AYL Lau, J Huang… - Stroke, 2024 - Am Heart Assoc
Vascular cognitive impairment (VCI) traditionally encompasses a variety of cerebrovascular
pathologies that contribute to varying levels of cognitive impairment, ranging from subtle to …

[HTML][HTML] Vessel density mapping of small cerebral vessels on 3D high resolution black blood MRI

MS Sarabi, SJ Ma, K Jann, JM Ringman, DJJ Wang… - Neuroimage, 2024 - Elsevier
Small cerebral blood vessels are largely inaccessible to existing clinical in vivo imaging
technologies. This study aims to present a novel analysis pipeline for vessel density …

Cerebral small vessel disease: early-life antecedents and long-term implications for the brain, aging, stroke, and dementia

EV Backhouse, JP Boardman, JM Wardlaw - Hypertension, 2024 - Am Heart Assoc
Cerebral small vessel disease is common in older adults and increases the risk of stroke,
cognitive impairment, and dementia. While often attributed to midlife vascular risk factors …

Biomarkers of Alzheimer's disease and cerebrovascular disease in relation to depressive symptomatology in individuals with subjective cognitive decline

M Zapater-Fajarí, P Diaz-Galvan… - The Journals of …, 2024 - academic.oup.com
Background Subjective cognitive decline (SCD) has gained recent interest as a potential
harbinger of neurodegenerative diseases such as Alzheimer's disease (AD) and …

Mediation of age and Thrombectomy outcome by neuroimaging markers of frailty in patients with stroke

F Benali, N Singh, J Fladt… - JAMA Network …, 2024 - jamanetwork.com
Importance Age is a leading predictor of poor outcomes after brain injuries like stroke. The
extent to which age is associated with preexisting burdens of brain changes, visible on …

Late-Life High Blood Pressure and Enlarged Perivascular Spaces in the Putaminal Regions of Community-Dwelling Japanese Older Persons

A Tachibana, J Iga, Y Tatewaki… - Journal of Geriatric …, 2024 - journals.sagepub.com
Background Enlarged perivascular spaces (EPVS) of the brain may be involved in dementia,
such as Alzheimer's disease and cerebral small vessel disease (CSVD). Hypertension has …

Research advancements on the correlation between spontaneous intracerebral Hemorrhage of different Etiologies and imaging markers of cerebral small vessel …

YT Liu, CY Lei, LM Zhong - Neuropsychiatric Disease and …, 2024 - Taylor & Francis
Objective The purpose of this review is to identify the correlation between ICH and CSVD
imaging markers under SMASH-U classification by searching and analyzing a large number …

[HTML][HTML] A Closer Look at the Perivascular Unit in the Development of Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes Mellitus

MR Hayden - Biomedicines, 2024 - mdpi.com
The recently described perivascular unit (PVU) resides immediately adjacent to the true
capillary neurovascular unit (NVU) in the postcapillary venule and contains the normal …

Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia

M Sargurupremraj, A Soumaré, JC Bis… - JAMA Network …, 2024 - jamanetwork.com
Importance Vascular disease is a treatable contributor to dementia risk, but the role of
specific markers remains unclear, making prevention strategies uncertain. Objective To …