Nutrition, Other Environmental Influences, and Genetics in the Determination of Human Stature

JC Lui, AC Palmer, P Christian - Annual Review of Nutrition, 2024 - annualreviews.org
Linear growth during three distinct stages of life determines attained stature in adulthood:
namely, in utero, early postnatal life, and puberty and the adolescent period. Individual host …

Pediatric brain tumors in sub-Saharan Africa: a systematic review and meta-analysis

AD Nyalundja, US Kanmounye, C Karekezi… - Journal of …, 2024 - thejns.org
OBJECTIVE Brain tumors are a global problem, leading to higher cancer-related morbidity
and mortality rates in children. Despite the progressive though slow advances in neuro …

Genomic investigation on genes related to mercury metabolism in Amazonian indigenous populations

VHV Carvalho, JCG Rodrigues, LWMS Vinagre… - Science of The Total …, 2024 - Elsevier
Studies have identified elevated levels of mercury in Amazonian Indigenous individuals,
highlighting them as one of the most exposed to risks. In the unique context of the Brazilian …

[HTML][HTML] Narrative Review Explaining the Role of HLA-A, -B, and -C Molecules in COVID-19 Disease in and around Africa

L Naidoo, T Arumugam, V Ramsuran - Infectious Disease Reports, 2024 - mdpi.com
The coronavirus disease 2019 (COVID-19) has left a devasting effect on various regions
globally. Africa has exceptionally high rates of other infectious diseases, such as …

Genetic association and transferability for urinary albumin-creatinine ratio as a marker of kidney disease in four Sub-Saharan African populations and non-continental …

JT Brandenburg, WC Chen, PR Boua… - Frontiers in …, 2024 - frontiersin.org
Background Genome-wide association studies (GWAS) have predominantly focused on
populations of European and Asian ancestry, limiting our understanding of genetic factors …

[HTML][HTML] Characterizing genetic profiles for high triglyceride levels in US patients of African ancestry

L Jiang, S Gangireddy, AL Dickson, Y Xin, C Yan… - Journal of Lipid …, 2024 - Elsevier
Hypertriglyceridemia (HTG) is a common cardiovascular risk factor characterized by
elevated circulating triglyceride (TG) levels. Researchers have assessed the genetic factors …

[HTML][HTML] Towards pharmacogenomics-guided tuberculosis (TB) therapy: N-acetyltransferase-2 genotypes among TB-infected Kenyans of mixed ethnicity

LN Njagi, JO Mecha, MW Mureithi, LE Otieno… - BMC Medical …, 2024 - Springer
Abstract Background Though persons of African descent have one of the widest genetic
variability, genetic polymorphisms of drug-metabolising enzymes such as N …

No Association Between AGT Gene Polymorphisms with Hypertension in a South African Population

JR Sharma, H Fokkens, R Laubscher… - Diabetes, Metabolic …, 2024 - Taylor & Francis
Purpose Hypertension is a leading cause of cardiovascular-related morbidity and mortality
worldwide, with a prevalence increasing at an alarming rate in both middle-and low-income …

Making glaucoma genetic studies more diverse

DA Mackey, SE Staffieri - Cell, 2024 - cell.com
Although the blinding eye disease glaucoma is more common in people of African ancestry,
previous genetic studies predominantly involved European subjects. In this issue of Cell …

[HTML][HTML] Alzheimer Disease Associated Loci: APOE Single Nucleotide Polymorphisms in Marmara Region

AB Ismail, MS Dundar, CO Erguzeloglu, MC Ergoren… - Biomedicines, 2024 - mdpi.com
Alzheimer's disease (AD) is a major global health challenge, especially among individuals
aged 65 or older. According to population health studies, Turkey has the highest AD …