The rapid and sensitive detection of pathogenic bacteria is becoming increasingly important
for the timely prevention of contamination and the treatment of infections. Biosensors based …

Functional nucleic acids (FNAs) have attracted increasing attention in recent years due to
their diverse physiological functions. The understanding of their conformational recognition …

The cell membrane exhibits a remarkable complexity of lipids and proteins that dynamically
segregate into distinct domains to coordinate various cellular functions. The ability to …

Chemical modification of aptamers is an important step to improve their performance and
stability in biological media. This can be performed either during their identification (mod …

Innovating the design of chimeric antigen receptors (CARs) beyond conventional structures
would be necessary to address the challenges of efficacy, safety, and applicability in T cell …

In multicellular organisms, individual cells are coordinated through complex communication
networks to accomplish various physiological tasks. Aiming to establish new biological …

Molecular profiling of cell-surface proteins is a powerful strategy for precise cancer
diagnosis. While mass cytometry (MC) enables synchronous detection of over 40 cellular …

Ebola viral disease (EVD) is a highly infectious and potentially fatal illness with a case
fatality rate ranging from 25% to 90%. To effectively control its spread, there is a need for …

Molecular engineering enables the creation of aptamers with novel functions, but the
prerequisite is a deep understanding of their structure and recognition mechanism. The …

The rapid and sensitive detection of pathogenic bacteria is becoming increasingly important
for the timely prevention of contamination and treatment of infections. Biosensors based on …