Oxidative stress in Alzheimer's disease: current knowledge of signaling pathways and therapeutics
Alzheimer's disease's pathophysiology is still a conundrum. Growing number of evidences
have elucidated the involvement of oxidative stress in the pathology of AD rendering it a …
have elucidated the involvement of oxidative stress in the pathology of AD rendering it a …
The role of Nrf2 signaling pathways in nerve damage repair
A Abdolmaleki, A Karimian, SM Khoshnazar… - Toxicology …, 2024 - academic.oup.com
The protein, Nuclear factor-E2-related factor 2 (Nrf2), is a transitory protein that acts as a
transcription factor and is involved in the regulation of many cytoprotective genes linked to …
transcription factor and is involved in the regulation of many cytoprotective genes linked to …
Neuroprotective potential of Betulinic acid against TIO2NP induced neurotoxicity in zebrafish
K Kaur, RK Narang, S Singh - International Immunopharmacology, 2024 - Elsevier
Betulinic acid (BA) is a natural triterpenoid extracted from Bacopa monnieri. BA has been
reported to be used as a neuroprotective agent, but their molecular mechanisms are still …
reported to be used as a neuroprotective agent, but their molecular mechanisms are still …
p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model
L Feng, C Wang, C Zhang, W Zhang… - Neural Regeneration …, 2024 - journals.lww.com
Glutamate excitotoxicity has been shown to play an important role in glaucoma, and
glutamate can induce ferroptosis. The p38 mitogenactivated protein kinase (MAPK) pathway …
glutamate can induce ferroptosis. The p38 mitogenactivated protein kinase (MAPK) pathway …
In silico Evaluation of Ferulic Acid Based Multifunctional Conjugates as Potential Drug Candidates
HA Al-Btoush, MA Al-Sha'er - Medicinal Chemistry, 2024 - ingentaconnect.com
Background: Recent research has shown that ferulic acid (FA, trans-4-hydroxy-3-
methoxycinnamic acid) has remarkable antioxidant properties and a wide range of …
methoxycinnamic acid) has remarkable antioxidant properties and a wide range of …