Lilrb3 supports immunosuppressive activity of myeloid cells and tumor development
The existing T cell–centered immune checkpoint blockade therapies have been successful
in treating some but not all patients with cancer. Immunosuppressive myeloid cells, including …
in treating some but not all patients with cancer. Immunosuppressive myeloid cells, including …
[HTML][HTML] A disease-associated gene desert directs macrophage inflammation through ETS2
CT Stankey, C Bourges, LM Haag, T Turner-Stokes… - Nature, 2024 - nature.com
Increasing rates of autoimmune and inflammatory disease present a burgeoning threat to
human health. This is compounded by the limited efficacy of available treatments and high …
human health. This is compounded by the limited efficacy of available treatments and high …
Identification of the hybrid gene LILRB5-3 by long-read sequencing and implication of its novel signaling function
Leukocyte immunoglobulin (Ig)-like receptors (LILRs) on human chromosome 19q13. 4
encode 11 immunoglobulin superfamily receptors, exhibiting genetic diversity within and …
encode 11 immunoglobulin superfamily receptors, exhibiting genetic diversity within and …
[HTML][HTML] A novel method for multiple phenotype association studies based on genotype and phenotype network
Joint analysis of multiple correlated phenotypes for genome-wide association studies
(GWAS) can identify and interpret pleiotropic loci which are essential to understand …
(GWAS) can identify and interpret pleiotropic loci which are essential to understand …
Exploring the causal relationship between Takayasu arteritis and inflammatory bowel disease using Mendelian randomization
X Pang, H Yang, C Wang, S Tian - Immunologic Research, 2024 - Springer
Takayasu arteritis (TA) and inflammatory bowel disease (IBD) are two distinct diseases;
however, previous studies have reported many cases of IBD-TA coexistence. Additionally …
however, previous studies have reported many cases of IBD-TA coexistence. Additionally …
A pilot study of childhood-onset Takayasu arteritis using whole exome sequencing suggests oligogenic inheritance involving classical complement, collagen, and …
J Kabeerdoss, S Danda, P Srivastava, R Kerkhale… - Clinical …, 2024 - Springer
Takayasu arteritis (TA) is a chronic granulomatous inflammatory disease affecting the aorta
and its branches. Paediatric TA (pTA) may present from 6 months after birth till the …
and its branches. Paediatric TA (pTA) may present from 6 months after birth till the …
Современные подходы к терапии артериита Такаясу
ОН Егорова, ГМ Тарасова… - Современная …, 2024 - mrj.ima-press.net
Аннотация Артериит Такаясу (АТ)–хронический гранулематозный системный васкулит
с поражением крупных сосудов, требующий мультидисциплинарного подхода …
с поражением крупных сосудов, требующий мультидисциплинарного подхода …