Fixel-based analysis reveals tau-related white matter changes in early stages of Alzheimer's disease

K Ahmadi, JB Pereira, D van Westen… - Journal of …, 2024 - Soc Neuroscience
Several studies have shown white matter (WM) abnormalities in Alzheimer's disease (AD)
using diffusion tensor imaging (DTI). Nonetheless, robust characterization of WM changes …

Bridging Reduced Grip Strength and Altered Executive Function: Specific Brain White Matter Structural Changes in Patients with Alzheimer's Disease

SW Liu, XT Ma, S Yu, XF Weng, M Li, J Zhu… - … Interventions in Aging, 2024 - Taylor & Francis
Objective To investigate the correlation between specific fiber tracts and grip strength and
cognitive function in patients with Alzheimer's disease (AD) by fixel-based analysis (FBA) …

Exploring individual fixel-based white matter abnormalities in epilepsy

R Mito, M Pedersen, H Pardoe, D Parker… - Brain …, 2024 - academic.oup.com
Diffusion MRI has provided insight into the widespread structural connectivity changes that
characterize epilepsies. Although syndrome-specific white matter abnormalities have been …

[HTML][HTML] Conduction velocity, G-ratio, and extracellular water as microstructural characteristics of autism spectrum disorder

BT Newman, Z Jacokes, S Venkadesh, SJ Webb… - Plos one, 2024 - journals.plos.org
The neuronal differences contributing to the etiology of autism spectrum disorder (ASD) are
still not well defined. Previous studies have suggested that myelin and axons are disrupted …

TractGeoNet: A geometric deep learning framework for pointwise analysis of tract microstructure to predict language assessment performance

Y Chen, LR Zekelman, C Zhang, T Xue, Y Song… - Medical Image …, 2024 - Elsevier
We propose a geometric deep-learning-based framework, TractGeoNet, for performing
regression using diffusion magnetic resonance imaging (dMRI) tractography and associated …

Spatio-angular convolutions for super-resolution in diffusion mri

M Lyon, P Armitage, MA Álvarez - Advances in Neural …, 2024 - proceedings.neurips.cc
Diffusion MRI (dMRI) is a widely used imaging modality, but requires long scanning times to
acquire high resolution datasets. By leveraging the unique geometry present within this …

Longitudinal fibre-specific white matter damage predicts cognitive decline in multiple sclerosis

I Koubiyr, EA Krijnen, AJC Eijlers, I Dekker… - Brain …, 2024 - academic.oup.com
During the course of multiple sclerosis, many patients experience cognitive deficits which
are not simply driven by lesion number or location. By considering the full complexity of …

[HTML][HTML] Novel approaches to assessing upper motor neuron dysfunction in motor neuron disease/amyotrophic lateral sclerosis: IFCN handbook chapter

T Dharmadasa, N Pavey, S Tu, P Menon… - Clinical …, 2024 - Elsevier
Identifying upper motor neuron (UMN) dysfunction is fundamental to the diagnosis and
understanding of disease pathogenesis in motor neuron disease (MND). The clinical …

White Matter Microstructural Underpinnings of Mild Behavioral Impairment in Parkinson's Disease

O Monchi, GD Pinilla‐Monsalve, H Almgren… - Movement …, 2024 - Wiley Online Library
Abstract Background Patients with Parkinson's disease (PD) experience changes in
behavior, personality, and cognition that can manifest even in the initial stages of the …

Longitudinal microstructural alterations surrounding subcortical ischemic stroke lesions detected by free‐water imaging

FL Nägele, M Petersen, C Mayer… - Human Brain …, 2024 - Wiley Online Library
In this study we explore the spatio‐temporal trajectory and clinical relevance of
microstructural white matter changes within and beyond subcortical stroke lesions detected …