Irisin is a hormone that is produced mainly by skeletal muscles in response to exercise. It
has been found to have a close correlation with obesity and diabetes mellitus for its energy …

Cardiovascular calcification is a significant public health issue whose pathophysiology is not
fully understood. NOR-1 regulates critical processes in cardiovascular remodeling, but its …

One mechanism to regulate pathological vascular calcification (VC) is its active inhibition.
Loss or inactivation of endogenic inhibitors is a major inductor of VC. Such inhibitors are …

We conducted a systematic search across medical databases, including PubMed, Web of
Science, EMBASE, and Cochrane Library, up to March 2023. A total of 1944 subjects or …

The global derangement of mineral metabolism that accompanies chronic kidney disease
(CKD-MBD) is a major driver of the accelerated mortality for individuals with kidney disease …

Background and Objectives: Brachial–ankle pulse wave velocity (baPWV) is an established
independent risk factor for cardiovascular events, cardiovascular mortality, and all-cause …

Introduction Vascular calcification is an intervenable factor in the pathophysiology of
cardiovascular disease. Treatment‐related factors might worsen the arterial stiffness in …

Objective: To investigate the correlation of serum osteopontin levels with disease severity
and prognosis in patients with acute cerebral infarction. Methods: This retrospective analysis …

目的探讨终末期肾病(ESRD) 患者心脏瓣膜钙化(CVC) 特点及其与25 羟维生素D [25 (OH) D]
缺乏的相关性. 方法纳入于我院治疗的ESRD 患者, 采用超声心动图评估主动脉瓣钙化(AVC) …

Annexins are Ca 2+-and lipid-binding proteins involved in Ca 2+ homeostasis in bone cells
and in extracellular vesicles. Annexins have been studied at the Nencki Institute since early …