Neutrophils are the most abundant innate immune cells. Multiple mechanisms allow them to
engage a wide range of metabolic pathways for biosynthesis and bioenergetics for …

Growing evidence supports the suggestion that the peripheral immune system plays a role
in different pathologies associated with cognitive impairment, such as vascular dementia …

Antibodies can initiate lung injury in a variety of disease states such as autoimmunity,
transfusion reactions, or after organ transplantation, but the key factors determining in vivo …

Neutrophils, the most abundant and efficient defenders against pathogens, exert opposing
functions across cancer types. However, given their short half-life, it remains challenging to …

Neutrophils are one of the first responders to infection and are a key component of the
innate immune system through their ability to phagocytose and kill invading pathogens …

Background Neutrophils are important in the pathophysiology of coronavirus disease 2019
(COVID-19), but the molecular changes contributing to altered neutrophil phenotypes …

Time-of-day significantly influences the severity and incidence of stroke. Evidence has
emerged not only for circadian governance over stroke risk factors, but also for important …

The immune system is built to counteract unpredictable threats, yet it relies on predictable
cycles of activity to function properly. Daily rhythms in immune function are an expanding …

Neutrophils rapidly respond to inflammation and infection, but to which degree their
functional trajectories after mobilization from the bone marrow are shaped within the …

Infections, cardiovascular disease, and cancer are major causes of disease and death
worldwide. Neutrophils are inescapably associated with each of these health concerns, by …