Background Prion diseases, also known as transmissible spongiform encephalopathies
(TSEs) remain one of the deleterious disorders, which have affected several animal species …

Prion-like proteins (PrLPs) have emerged as beneficial molecules with implications in
adaptive responses. These proteins possess a conserved prion-like domain (PrLD) which is …

Neurodegenerative diseases are characterised by neuronal loss and abnormal deposition
of pathological proteins in the nervous system. Among the most common neurodegenerative …

A case of Creutzfeldt-Jakob Disease (CJD), a rare prion disease, posted for surgery is a
clinically challenging scenario for an anesthesiologist. In addition to weighing in the …

Neurodegenerative diseases affect the neuronal system, with irreversible loss of neurons.
Many factors play a role in the development of NDD and till now no conclusive cure is …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterised by the loss of motor neurons. Mutations in the superoxide dismutase 1 (SOD1) …

Prion protein (PrP C) interacts with 38 to 42 amino acid amyloid-β (Aβ) peptides released by
proteolytic processing of amyloid precursor protein (APP). Our laboratory previously …

Prions are infectious proteins that cause rare but invariably fatal neurodegenerative
diseases in humans and other mammals. Sporadic Creutzfeldt-Jakob disease (sCJD) is the …

Šī promocijas darbamērķis izpētīt proteīnus, kas regulē infekcijas aģentu mijiedarbību ar
saimniekorganisma iekšējo vidi. Lai sasniegtu šo mērķi, tika pētītitrīs proteīni no diviem …

Alzheimer's disease is the leading cause of dementia and is creating a growing economic
and social burden on the aging global population. The drugs approved for the treatment of …