Abstract The utilization of Platinum (Pt)-based drugs has significantly transformed the
landscape of cancer chemotherapy, serving as highly effective anticancer agents. However …

Colorectal cancer (CRC) is a common and deadly form of cancer, leading to the need for
new therapeutic targets and strategies for treatment. Recent studies have shown the cGAS …

Methods accurately predicting the responses of colorectal cancer (CRC) and colorectal
cancer liver metastasis (CRLM) to personalized chemotherapy remain limited due to tumor …

Background Randomized clinical trials have defined the survival advantage with the
addition of biologic drugs to chemotherapy in patients with metastatic colorectal cancer …

While previous studies have indicated the involvement of Isthmin 1 (ISM1), a secreted
protein, in cancer development, the precise mechanisms have remained elusive. In this …

The adsorption of 5-fluorouracil (5FU) on Watson–Crick (WC) base pairs and Hoogsteen
(HT) base pairs has been studied using the dispersion-corrected density functional theory …

The relationship between drug‐induced liver injury and liver metastasis of colorectal cancer
and the underlying mechanisms are not well understood. In this study, we used carbon …

Background Colorectal cancer remains the third leading cause of cancer-related mortality in
the United States. This study evaluates the causes of death in patients operated on for …

Background: Metastatic colorectal cancer (mCRC) is a major health burden worldwide and a
growing challenge in Asian countries. Treatment options include chemotherapy and …

Oral fluoropyrimidines (FUs) have certain advantages over intravenous FUs, such as longer
intervals between outpatient visits, no requirement for central venous port (CVP) …