Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2
Long COVID (LC) occurs after at least 10% of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …
coronavirus 2 (SARS-CoV-2) infections, yet its etiology remains poorly understood. We used …
Metabolomic and immune alterations in long COVID patients with chronic fatigue syndrome
Introduction A group of SARS-CoV-2 infected individuals present lingering symptoms,
defined as long COVID (LC), that may last months or years post the onset of acute disease …
defined as long COVID (LC), that may last months or years post the onset of acute disease …
The role of cytokines and Molecular pathways in Lung Fibrosis following SARS-CoV-2 infection: a physiopathologic (re) view
SARS-CoV-2 infection is a significant health concern that needs to be addressed not only
during the initial phase of infection but also after hospitalization. This is the consequence of …
during the initial phase of infection but also after hospitalization. This is the consequence of …
Transcriptomic profiling of peripheral blood cells in HPV‐associated carcinoma patients receiving combined valproic acid and avelumab
N Bozorgmehr, H Syed, S Mashhouri… - Molecular …, 2024 - Wiley Online Library
Human papillomavirus (HPV)‐associated cancer continues to evade the immune system by
promoting a suppressive tumor microenvironment. Therefore, immunotherapy appears to be …
promoting a suppressive tumor microenvironment. Therefore, immunotherapy appears to be …
The Role of Coinhibitory Receptors in B Cell Dysregulation in SARS-CoV-2–Infected Individuals with Severe Disease
Severe SARS-CoV-2 infection is associated with significant immune dysregulation involving
different immune cell subsets. In this study, when analyzing critically ill COVID-19 patients …
different immune cell subsets. In this study, when analyzing critically ill COVID-19 patients …
[HTML][HTML] The elevation of plasma galectin-9 levels in patients with psoriasis and its associations with inflammatory and immune checkpoint molecules in skin tissues
H Chagan-Yasutan, N He, S Arlud, J Fang, T Hattori - Human Immunology, 2024 - Elsevier
Psoriasis is a chronic, immune-mediated disorder that mainly affects the skin, with an
estimated global prevalence of 2–3%. Galectin-9 (Gal-9) is a β-galactoside-binding lectin …
estimated global prevalence of 2–3%. Galectin-9 (Gal-9) is a β-galactoside-binding lectin …
[HTML][HTML] Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome
A substantial number of patients recovering from acute SARS-CoV-2 infection present
serious lingering symptoms, often referred to as long COVID (LC). However, a subset of …
serious lingering symptoms, often referred to as long COVID (LC). However, a subset of …
SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9
Y Luo, Z Zhang, J Ren, C Dou, J Wen, Y Yang… - Frontiers in …, 2024 - frontiersin.org
Background Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), as a
typical tumor marker, has been found to exert immunomodulatory effects in many diseases …
typical tumor marker, has been found to exert immunomodulatory effects in many diseases …
Plasma galectin-9 levels correlate with blood monocyte turnover and predict simian/human immunodeficiency virus disease progression
L Zablocki-Thomas, A Ardeshir, N Takahashi… - Translational Medicine …, 2024 - Springer
Background Late-stage human immunodeficiency virus (HIV) infection is typically
characterized by low CD4+ T-cell count. We previously showed that profound changes in the …
characterized by low CD4+ T-cell count. We previously showed that profound changes in the …
[HTML][HTML] Knockdown of Galectin-9 alleviates rheumatoid arthritis through suppressing TNF-α-induced activation of fibroblast-like synoviocytes
Q Jia, Q Che, X Zhang, J Chen, C Ren, Y Wu… - Biochemical …, 2024 - Elsevier
Abstract The role of Galectin-9 (Gal-9) in the pathogenesis of rheumatoid arthritis (RA)
remains unclear. This study aimed to investigate the mechanism of action and therapeutic …
remains unclear. This study aimed to investigate the mechanism of action and therapeutic …