Impact of Ebola virus nucleoprotein on VP40 virus-like particle production: a computational approach

X Liu, RV Stahelin, E Pienaar - Communications Biology, 2024 - nature.com
Ebola virus (EBOV) matrix protein VP40 can assemble and bud as virus-like particles (VLPs)
when expressed alone in mammalian cells. Nucleoprotein (NP) could be recruited to VLPs …

Molecular modeling and simulation studies of SELEX-derived high-affinity DNA aptamers to the Ebola virus nucleoprotein

DR Martin, AT Mutombwera, AM Madiehe… - Journal of …, 2024 - Taylor & Francis
Ebola viral disease (EVD) is a highly infectious and potentially fatal illness with a case
fatality rate ranging from 25% to 90%. To effectively control its spread, there is a need for …

Structural basis of Ebola virus nucleocapsid assembly and functions

Y Fujita-Fujiharu, S Hu, A Hirabayashi, Y Takamatsu… - bioRxiv, 2024 - biorxiv.org
The Ebola virus, a member of the Filoviridae family, causes severe hemorrhagic fever in
humans. Filamentous virions contain a helical nucleocapsid responsible for genome …