[HTML][HTML] Treatments for COVID-19
HS Andrews, JD Herman… - Annual Review of …, 2024 - annualreviews.org
The treatment for COVID-19 has evolved rapidly since the start of the pandemic and now
consists mainly of antiviral and immunomodulatory agents. Antivirals, such as remdesivir …
consists mainly of antiviral and immunomodulatory agents. Antivirals, such as remdesivir …
[HTML][HTML] The impact of formaldehyde exposure on lung inflammatory disorders: Insights into asthma, bronchitis, and pulmonary fibrosis
Lung inflammatory disorders are a major global health burden, impacting millions of people
and raising rates of morbidity and death across many demographic groups. An industrial …
and raising rates of morbidity and death across many demographic groups. An industrial …
[HTML][HTML] Adjuvant-dependent impact of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus
JA Dillard, SA Taft-Benz, AC Knight… - Nature …, 2024 - nature.com
Whole virus-based inactivated SARS-CoV-2 vaccines adjuvanted with aluminum hydroxide
have been critical to the COVID-19 pandemic response. Although these vaccines are …
have been critical to the COVID-19 pandemic response. Although these vaccines are …
[HTML][HTML] Multi-omics analysis reveals COVID-19 vaccine induced attenuation of inflammatory responses during breakthrough disease
RE Drury, S Camara, I Chelysheva, S Bibi… - Nature …, 2024 - nature.com
The immune mechanisms mediating COVID-19 vaccine attenuation of COVID-19 remain
undescribed. We conducted comprehensive analyses detailing immune responses to SARS …
undescribed. We conducted comprehensive analyses detailing immune responses to SARS …
Even one dose of tocilizumab could hinder bad prognosis of cytokines storm in COVID-19 patients
MAS Elgohary, A Ali, SJ Alarfaj, H Shahin, AI Zaki… - Cytokine, 2024 - Elsevier
Severe COVID-19 pneumonia is a principal cause of death due to cascade of hyper
inflammatory condition that leading to lung damage. Therefore, an effective therapy to …
inflammatory condition that leading to lung damage. Therefore, an effective therapy to …
[HTML][HTML] No evidence for enhanced disease with human polyclonal SARS-CoV-2 antibody in the ferret model
Since SARS-CoV-2 emerged in late 2019, it spread from China to the rest of the world. An
initial concern was the potential for vaccine-or antibody-dependent enhancement (ADE) of …
initial concern was the potential for vaccine-or antibody-dependent enhancement (ADE) of …
Characterization and immunogenicity assessment of MERS-CoV pre-fusion spike trimeric oligomers as vaccine immunogen
R Ahuja, P Vishwakarma, S Raj, V Kumar… - Human Vaccines & …, 2024 - Taylor & Francis
Middle East respiratory syndrome coronavirus (MERS-CoV) is a lethal beta-coronavirus that
emerged in 2012. The virus is part of the WHO blueprint priority list with a concerning fatality …
emerged in 2012. The virus is part of the WHO blueprint priority list with a concerning fatality …
[HTML][HTML] Pyrogenic and inflammatory mediators are produced by polarized M1 and M2 macrophages activated with D-dimer and SARS-CoV-2 spike immune …
YJ Park, D Acosta, MR Hoq, S Khurana, H Golding… - Cytokine, 2024 - Elsevier
Lung macrophages are the first line of defense against invading respiratory pathogens
including SARS-CoV-2, yet activation of macrophage in the lungs can lead to …
including SARS-CoV-2, yet activation of macrophage in the lungs can lead to …
[HTML][HTML] Physicochemical properties-based hybrid machine learning technique for the prediction of SARS-CoV-2 T-cell epitopes as vaccine targets
SNH Bukhari, E Elshiekh, M Abbas - PeerJ Computer Science, 2024 - peerj.com
Majority of the existing SARS-CoV-2 vaccines work by presenting the whole pathogen in the
attenuated form to immune system to invoke an immune response. On the other hand, the …
attenuated form to immune system to invoke an immune response. On the other hand, the …
[HTML][HTML] From Detection to Protection: Antibodies and Their Crucial Role in Diagnosing and Combatting SARS-CoV-2
Understanding the antibody response to SARS-CoV-2, the virus responsible for COVID-19,
is crucial to comprehending disease progression and the significance of vaccine and …
is crucial to comprehending disease progression and the significance of vaccine and …