Antibody and B cell responses to SARS-CoV-2 infection and vaccination: the end of the beginning
As the COVID-19 pandemic has evolved during the past years, interactions between human
immune systems, rapidly mutating and selected SARS-CoV-2 viral variants, and effective …
immune systems, rapidly mutating and selected SARS-CoV-2 viral variants, and effective …
A Mini-Review on the Common Antiviral Drug Targets of Coronavirus
J Wang, Q Zhu, X Xing, D Sun - Microorganisms, 2024 - mdpi.com
Coronaviruses in general are a zoonotic pathogen with significant cross-species
transmission. They are widely distributed in nature and have recently become a major threat …
transmission. They are widely distributed in nature and have recently become a major threat …
Severe acute respiratory syndrome Coronavirus-2 GenoAnalyzer and mutagenic anomaly detector using FCMFI and NSCE
In order to deepen our understanding of the virus and help guide the creation of efficient
therapies, this study uses artificial intelligence tools to thoroughly explore the genetic …
therapies, this study uses artificial intelligence tools to thoroughly explore the genetic …
An alphacoronavirus polymerase structure reveals conserved replication factor functions
TK Anderson, PJ Hoferle, KJ Chojnacki… - Nucleic Acids …, 2024 - academic.oup.com
Coronaviruses are a diverse subfamily of viruses containing pathogens of humans and
animals. This subfamily of viruses replicates their RNA genomes using a core polymerase …
animals. This subfamily of viruses replicates their RNA genomes using a core polymerase …
Sulfated glycans inhibit the interaction of MERS-CoV receptor binding domain with heparin
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus with high
contagion and mortality rates. Heparan sulfate proteoglycans (HSPGs) are ubiquitously …
contagion and mortality rates. Heparan sulfate proteoglycans (HSPGs) are ubiquitously …
Immunological aspects of emerging and re-emerging zoonoses
W Wang, J Li, Y Liang, W Gong - Frontiers in immunology, 2024 - frontiersin.org
Zoonoses, a group of diseases that are transmitted between animals and humans, are
considered as the most prevalent infections in humans (1). They present substantial global …
considered as the most prevalent infections in humans (1). They present substantial global …
Prevalence of Obesity and its Effects in Patients With COVID-19: A Systematic Review and Meta-analysis
Background: Coronavirus disease 2019 (COVID-19) is an emerging infectious disease
worldwide. Obesity has been proven to increase the susceptibility of an individual to …
worldwide. Obesity has been proven to increase the susceptibility of an individual to …
Study of key residues in MERS-CoV and SARS-CoV-2 main proteases for resistance against clinically applied inhibitors nirmatrelvir and ensitrelvir
L Krismer, H Schöppe, S Rauch, D Bante, B Sprenger… - npj Viruses, 2024 - nature.com
Abstract The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an epidemic,
zoonotically emerging pathogen initially reported in Saudi Arabia in 2012. MERS-CoV has …
zoonotically emerging pathogen initially reported in Saudi Arabia in 2012. MERS-CoV has …
A Comparative Analysis of Molecular Biological Methods for the Detection of SARS-CoV-2 and Testing the In Vitro Infectivity of the Virus
K Shishkova, B Sirakova, S Shishkov, E Stoilova… - Microorganisms, 2024 - mdpi.com
The virus discovered in 2019 in the city of Wuhan, China, which was later identified as SARS-
CoV-2 and which spread to the level of a pandemic, put diagnostic methods to the test. Early …
CoV-2 and which spread to the level of a pandemic, put diagnostic methods to the test. Early …
Safety, immunogenicity and efficacy of Relcovax®, a dual receptor binding domain (RBD) and nucleocapsid (N) subunit protein vaccine candidate against SARS-CoV …
N Sathe, S Shaikh, M Bhavsar, L Parte, A Gadiparthi… - Vaccine, 2024 - Elsevier
Abstract SARS-CoV-2, severe acute respiratory syndrome coronavirus-2, causes
coronavirus disease-2019 (COVID-19). Mostly, COVID-19 causes respiratory symptoms that …
coronavirus disease-2019 (COVID-19). Mostly, COVID-19 causes respiratory symptoms that …