Background The positive effect of education on reducing all-cause adult mortality is known;
however, the relative magnitude of this effect has not been systematically quantified. The …

Background A critical and persistent challenge to global health and modern health care is
the threat of antimicrobial resistance (AMR). Previous studies have reported a …

Background Estimates of demographic metrics are crucial to assess levels and trends of
population health outcomes. The profound impact of the COVID-19 pandemic on …

Background Regular, detailed reporting on population health by underlying cause of death
is fundamental for public health decision making. Cause-specific estimates of mortality and …

Background Detailed, comprehensive, and timely reporting on population health by
underlying causes of disability and premature death is crucial to understanding and …

Background Hearing loss affects approximately 1· 6 billion individuals worldwide. Many
cases are preventable. We aimed to estimate the annual number of new hearing loss cases …

Background Accurate assessments of current and future fertility—including overall trends
and changing population age structures across countries and regions—are essential to help …

Background Sex and gender shape health. There is a growing body of evidence focused on
comprehensively and systematically examining the magnitude, persistence, and nature of …

Cellular senescence, a hallmark of aging, results in a senescence-associated secretory
phenotype (SASP) with an increased production of proinflammatory cytokines, growth …

Background Exacerbated by an aging population, musculoskeletal diseases are a chronic
and growing problem in the United States that impose significant health and economic …