Unmasking the NLRP3 inflammasome in dendritic cells as a potential therapeutic target for autoimmunity, cancer, and infectious conditions
Proper and functional immune response requires a complex interaction between innate and
adaptive immune cells, which dendritic cells (DCs) are the primary actors in this coordination …
adaptive immune cells, which dendritic cells (DCs) are the primary actors in this coordination …
Inflammasomes Are Influenced by Epigenetic and Autophagy Mechanisms in Colorectal Cancer Signaling
G Műzes, F Sipos - International Journal of Molecular Sciences, 2024 - mdpi.com
Inflammasomes contribute to colorectal cancer signaling by primarily inducing inflammation
in the surrounding tumor microenvironment. Its role in inflammation is receiving increasing …
in the surrounding tumor microenvironment. Its role in inflammation is receiving increasing …
Cryptotanshinone Inhibits Bladder Cancer Cell Malignant Progression in a Lipopolysaccharide‐Induced Inflammatory Microenvironment through NLRP3 Inhibition
C Tang, X Guo, Y Li, Y Yi, Z Tang… - Mediators of …, 2024 - Wiley Online Library
Background. Bladder cancer (BC) is one of the most common malignancies of the urogenital
system. This study assessed the nucleotide‐binding oligomerization domain and leucine …
system. This study assessed the nucleotide‐binding oligomerization domain and leucine …
Curcumin modulates purinergic signaling and inflammatory response in cutaneous metastatic melanoma cells
D Manica, GB da Silva, RA Narzetti, P Dallagnoll… - Purinergic …, 2024 - Springer
Cutaneous melanoma (CM) poses a therapeutic challenge due to its aggressive nature and
often limited response to conventional treatments. Exploring novel therapeutic targets is …
often limited response to conventional treatments. Exploring novel therapeutic targets is …
Transcription factor ASCL1 targets SLC6A13 to inhibit the progression of hepatocellular carcinoma via the glycine-inflammasome signaling
H Zhang, R Zong, H Wu, J Jiang, C Liu… - Biomolecules and …, 2024 - bjbms.org
The purpose of this research was to clarify the function of achaete-scute family bHLH
transcription factor 1 (ASCL1) and solute carrier family 6 member 13 (SLC6A13) in …
transcription factor 1 (ASCL1) and solute carrier family 6 member 13 (SLC6A13) in …