Roles of the medial and lateral orbitofrontal cortex in major depression and its treatment

B Zhang, ET Rolls, X Wang, C Xie, W Cheng… - Molecular …, 2024 - nature.com
We describe evidence for dissociable roles of the medial and lateral orbitofrontal cortex
(OFC) in major depressive disorder (MDD) from structure, functional activation, functional …

A neuroanatomical and cognitive model of impaired social behaviour in frontotemporal dementia

MA Rouse, RJ Binney, K Patterson, JB Rowe… - Brain, 2024 - academic.oup.com
Impaired social cognition is a core deficit in frontotemporal dementia (FTD). It is most
commonly associated with the behavioural-variant of FTD, with atrophy of the orbitofrontal …

Defining the r factor for post-trauma resilience and its neural predictors

SJH van Rooij, JL Santos, CA Hinojosa, TD Ely… - Nature Mental …, 2024 - nature.com
Although resilience is a dynamic process of recovery after trauma, in most studies it is
conceptualized as the absence of specific psychopathology following trauma. Here, using …

A systems identification approach using Bayes factors to deconstruct the brain bases of emotion regulation

K Bo, TE Kraynak, M Kwon, M Sun, PJ Gianaros… - Nature …, 2024 - nature.com
Cognitive reappraisal is fundamental to cognitive therapies and everyday emotion
regulation. Analyses using Bayes factors and an axiomatic systems identification approach …

Anatomo-functional basis of emotional and motor resonance elicited by facial expressions

M Del Vecchio, P Avanzini, M Gerbella, S Costa… - Brain, 2024 - academic.oup.com
Simulation theories predict that the observation of other's expressions modulates neural
activity in the same centers controlling their production. This hypothesis has been developed …

Noradrenergic regulation of cue-guided decision making and impulsivity is doubly dissociable across frontal brain regions

CS Chernoff, TJ Hynes, JD Schumacher… - …, 2024 - Springer
Rationale Win-paired stimuli can promote risk taking in experimental gambling paradigms in
both rats and humans. We previously demonstrated that atomoxetine, a noradrenaline …

Human ventromedial prefrontal cortex is necessary for prosocial motivation

PL Lockwood, J Cutler, D Drew, A Abdurahman… - Nature Human …, 2024 - nature.com
Ventromedial prefrontal cortex (vmPFC) is vital for decision-making. Functional
neuroimaging links vmPFC to processing rewards and effort, while parallel work suggests …

A vast space of compact strategies for effective decisions

T Ma, AM Hermundstad - Science Advances, 2024 - science.org
Inference-based decision-making, which underlies a broad range of behavioral tasks, is
typically studied using a small number of handcrafted models. We instead enumerate a …

Grid-like entorhinal representation of an abstract value space during prospective decision making

A Nitsch, MM Garvert, JLS Bellmund… - Nature …, 2024 - nature.com
How valuable a choice option is often changes over time, making the prediction of value
changes an important challenge for decision making. Prior studies identified a cognitive map …

[HTML][HTML] Perturbations in risk/reward decision making and frontal cortical catecholamine regulation induced by mild traumatic brain injury

CP Knapp, E Papadopoulos, JA Loweth… - Behavioural brain …, 2024 - Elsevier
Mild traumatic brain injury (mTBI) disrupts cognitive processes that influence risk taking
behavior. Little is known regarding the effects of repetitive mild injury (rmTBI) or whether …