Tissue biomarkers of immune checkpoint inhibitor therapy

F Davoudi, A Moradi, H Sadeghirad… - Immunology and Cell …, 2024 - Wiley Online Library
Cancer immunotherapy has been rejuvenated by the growing understanding of the immune
system's role in tumor activity over the past two decades. During cancer initiation and …

In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection

CW Tan, J Chen, N Liu, DD Bhuva, T Blick… - …, 2024 - thelancet.com
In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection -
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Omics-based profiles and biomarkers of respiratory infections: are we there yet?

JP Garcia, SE Evans - European Respiratory Journal, 2024 - Eur Respiratory Soc
Extract From the influenza pandemic of 1918–1919 to the most recent COVID-19 pandemic,
respiratory infections remain a leading cause of mortality worldwide [1, 2]. Concurrently, the …

DiSignAtlas: an atlas of human and mouse disease signatures based on bulk and single-cell transcriptomics

Z Zhai, Z Lin, X Meng, X Zheng, Y Du, Z Li… - Nucleic Acids …, 2024 - academic.oup.com
Molecular signatures are usually sets of biomolecules that can serve as diagnostic,
prognostic, predictive, or therapeutic markers for a specific disease. Omics data derived from …

Pre-Infection Innate Immunity Attenuates SARS-CoV-2 Infection and Viral Load in iPSC-Derived Alveolar Epithelial Type 2 Cells

S Kumar, J Granados, M Aceves, J Peralta… - Cells, 2024 - mdpi.com
A large portion of the heterogeneity in coronavirus disease 2019 (COVID-19) susceptibility
and severity of illness (SOI) remains poorly understood. Recent evidence suggests that …

Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures

N Stylianou, I Sebina, N Matigian… - Clinical & …, 2024 - Wiley Online Library
Abstract Objectives Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2)
virus infection in pregnancy is associated with higher incidence of placental dysfunction …

SARS-CoV-2 disrupts host gene networks: unveiling key hub genes as potential therapeutic targets for COVID-19 management

M Marta, M Maździarz, K Krawczyk, Ł Paukszto… - 2024 - researchsquare.com
Background Although the end of COVID-19 as a public health emergency was declared on
May 2023, still new cases of the infection are reported and the risk remains of new variants …

[PDF][PDF] Whole transcriptome profiling of placental pathobiology in SARS-CoV-2 pregnancies identifies placental dysfunction signatures

H Doehler, J Röhl, M Allenby, A Nam, L Pan… - scienceopen.com
Abstract Objectives. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus
infection in pregnancy is associated with higher incidence of placental dysfunction, referred …